Biotecnología
Biotecnología
Cell-Penetrating Peptides as Vehicles for Delivery of Therapeutic Nucleic Acids. Mechanisms and Application in Medicine
01/12/2023 -
Abstract Currently, nucleic acid therapeutics are actively developed for the treatment and prophylactic of metabolic disorders and oncological, inflammatory, and infectious...
Methods for Assessment of Nucleotide Excision Repair Efficiency
01/12/2023 -
Abstract Nucleotide excision repair (NER) is responsible for removing a wide variety of bulky adducts from DNA, thus contributing to the maintenance of genome stability. The...
Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA)
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
The weekly cycle of photosynthesis in Europe reveals the negative impact of particulate pollution on ecosystem productivity
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
The neurobiology of stress: Vulnerability, resilience, and major depression
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
Spatial -omics technologies: the new enterprise in 3D breast cancer models
01/12/2023 -
Engineered antibodies are essential tools for research and advanced pharmacy. In the development of therapeutics, antibodies are excellent candidates as they offer both target recognition and...
Microgravity Effects and Aging Physiology: Similar Changes or Common Mechanisms?
01/12/2023 -
Abstract Despite the use of countermeasures (including intense physical activity), cosmonauts and astronauts develop muscle atony and atrophy, cardiovascular system failure,...
Biochemical and Ultrastructural Changes in Wheat Plants during Drought Stress
01/12/2023 -
Abstract Drought severely slows down plant growth, decreases crop yield, and affects various physiological processes in plants. We examined four local bread wheat cultivars...
Generational differences in mental health trends in the twenty-first century
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
Ca2+ regulation of glutamate release from inner hair cells of hearing mice
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
Epigenetic switch reshapes epithelial progenitor cell signatures and drives inflammatory pathogenesis in hidradenitis suppurativa
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
SPA, a Stigma-style-transmitting tract Physical microenvironment Assay for investigating mechano-signaling in pollen tubes
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
Fighting the battle against evolution: designing genetically modified organisms for evolutionary stability
01/12/2023 -
PG (Box 1) integrates genomic and transcriptomic data to help identify novel peptides from mass spectrometry (MS) (see Glossary) based proteomic data; in turn, the proteomic data can be used to...
Presage, AstraZeneca Partner on Immuno-Oncology Drugs
01/12/2023 -
Presage's platform will be used in translational analysis to evaluate investigational bispecific antibody combinations.
DNA Instability in Neurons: Lifespan Clock and Driver of Evolution
01/12/2023 -
Abstract In the last ten years, the discovery of neuronal DNA postmitotic instability has changed the theoretical landscape in neuroscience and, more broadly, biology. In...
Differences in Structural Changes and Pathophysiological Effects of Low-Density Lipoprotein Particles upon Accumulation of Acylhydroperoxy Derivatives in Their Outer Phospholipid Monolayer or upon Modification of Apoprotein B-100 by Natural Dicarbonyls
01/12/2023 -
Abstract Nanoparticles of the lipid-transporting system of the organism, low-density lipoproteins (LDL) of blood plasma, are prone to free radical peroxidation with formation...
Sharing names and information: Incidental similarities between CEOs and analysts can lead to favoritism in information disclosure
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
Low- and high-frequency vibrations synergistically enhance singlet exciton fission through robust vibronic resonances
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
Variability in excess deaths across countries with different vulnerability during 2020–2023
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
Imaging tumor lactate is feasible for identifying intermediate-risk prostate cancer patients with postsurgical biochemical recurrence
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
