Biotecnología
Biotecnología
Lexeo Enters License Agreement for Friedreich Ataxia Treatment
25/04/2024 -
Aims to expedite development of investigational gene therapy candidate LX2006 for the treatment of FA cardiomyopathy.
Advances in Therapeutic Cancer Vaccines, Their Obstacles, and Prospects Toward Tumor Immunotherapy
22/04/2024 -
Abstract Over the past few decades, cancer immunotherapy has experienced a significant revolution due to the advancements in immune checkpoint inhibitors (ICIs) and adoptive cell...
Studies on Treatment Within the Scope of Medical Biotechnology for Pancreatic Diseases
22/04/2024 -
Abstract The pancreas is made of two compartments: the exocrine pancreas, a source of digestive enzymes, and the endocrine islets which produce vital hormones. Distinct diseases...
Prediction of Prospective Mutational Landscape of SARS-CoV-2 Spike ssRNA and Evolutionary Basis of Its Host Interaction
22/04/2024 -
Abstract Booster doses are crucial against severe COVID-19, as rapid virus mutations and variant emergence prolong the pandemic crisis. The virus’s quick evolution, short...
WTAP-mediated N6-methyladenine Modification of circEEF2 Promotes Lung Adenocarcinoma Tumorigenesis by Stabilizing CANT1 in an IGF2BP2-dependent Manner
22/04/2024 -
Abstract N6-methyladenosine (m6A) is a common posttranscriptional RNA modification and plays an important role in cancer biology. Circular RNAs (circRNAs) are also reported to...
Exploring the Role of Ferroptosis-Related Circular RNAs in Subarachnoid Hemorrhage
22/04/2024 -
Abstract Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular event associated with high mortality and significant morbidity. Recent studies have highlighted the...
Pyrroloquinoline quinone protects against murine hepatitis virus strain 3-induced fulminant hepatitis by inhibiting the Keap1/Nrf2 signaling
22/04/2024 -
Abstract Fulminant hepatitis (FH) is a life-threatening clinical liver syndrome characterized by substantial hepatocyte necrosis and severe liver damage. FH is typically...
YTHDC1-Mediated lncRNA MSC-AS1 m6A Modification Potentiates Laryngeal Squamous Cell Carcinoma Development via Repressing ATXN7 Transcription
22/04/2024 -
Abstract Laryngeal squamous cell carcinoma (LSCC) has the highest mortality rate among head and neck squamous cell carcinoma. This study was designed to investigate the biological...
Correlation Between Serum 1,25(OH)2D3, Serum Phosphorus, and Parathyroid Hormone and Parathyroid Function After Central Lymph Node Dissection in Patients with Papillary Thyroid Carcinoma
22/04/2024 -
Abstract This work was to demonstrate the relationship between serum 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), serum phosphorus (SP), and parathyroid hormone (PTH) and parathyroid...
Mechanisms of Ferroptosis-Related Genes in Gallbladder Cancer Based on Bioinformatics Analysis
22/04/2024 -
Abstract Gallbladder Cancer (GBC) is a lethal malignancy with limited treatment options and poor prognosis. Recent studies have emphasized the role of ferroptosis, a regulated...
Ferring and SK Pharmteco Partner to Increase Production of ADSTILADRIN
19/04/2024 -
Will scale up commercial manufacturing capacity for the drug substance of Ferring’s intravesical non-replicating gene therapy.
Stable two- and three-dimensional cholangiocyte culture systems from extrahepatic bile ducts of biliary atresia patients: use of structural and functional bile duct epithelium models for in vitro analyses
16/04/2024 -
Abstract We herein report two- (2D) and three-dimensional (3D) culture methods of cholangiocytes originating from extrahepatic bile ducts of biliary atresia (BA) patients. Cells...
The effect of TFAP2A/ANXA8 axis on ferroptosis of cervical squamous cell carcinoma (CESC) in vitro
16/04/2024 -
Abstract Potential role and associated mechanisms of Annexin A8 (ANXA8), a member of the Annexins family, in cervical squamous cell carcinoma (CESC) are still unclear, despite...
Deciphering Ferroptosis: From Molecular Pathways to Machine Learning-Guided Therapeutic Innovation
16/04/2024 -
Abstract Ferroptosis is a unique form of cell death reliant on iron and lipid peroxidation. It disrupts redox balance, causing cell death by damaging the plasma membrane, with...
Recombinant Amidases: Recent Insights and its Applications in the Production of Industrially Important Fine Chemicals
16/04/2024 -
Abstract The current research for the synthesis of industrially important fine chemicals is more inclined towards developing enzyme-based processes. The biotransformation...
Expression and processing of mature human frataxin after gene therapy in mice
16/04/2024 -
https://www.nature.com/articles/s41598-024-59060-0
CSafe Launches Three New Cold Chain Technologies
16/04/2024 -
Multi-Use Dewars designed to serve cell and gene therapy market, CSafe Connect Control Tower monitoring service, and Silverpod MAX RE.
Session at AAPS National Biotechnology Conference to Cover Gene & Therapy Market
16/04/2024 -
‘Cell and Gene Therapies at the Intersection of Business and Science,’ will take place on May 14 at 9:30 a.m. in San Francisco.
Ascend Acquires Florida Facility and Expertise, Bolstering Gene Therapy Development
10/04/2024 -
Enters long-term partnership with Beacon to continue manufacturing its products for clinical and commercial use.
Charles River & Axovia Partner to Support Development of Gene Therapies for Ciliopathies
10/04/2024 -
Axovia will leverage Charles River’s plasmid platform and expertise in plasmid DNA production to accelerate time to clinic.
Targeting biofilm infections in humans using small scale robotics
08/04/2024 -
Nature often uses dynamically assembling multienzymatic complexes called metabolons to achieve spatiotemporal control of complex metabolic reactions. Researchers are aiming to mimic this strategy of...
