Biotecnología

Biotecnología

Interleukin 4 improved adipose-derived stem cells engraftment via interacting with fibro/adipogenic progenitors in dystrophic mice
01/12/2023 - Abstract Adipose-derived stem cells (ADSC) therapy shows promise as an effective treatment for dystrophinopathy. Fibro-/adipogenic progenitors (FAPs) play an essential role in...
Exosomes for CRISPR-Cas9 Delivery: The Cutting Edge in Genome Editing
01/12/2023 - Abstract Gene mutation correction was challenging until the discovery of clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein (Cas)....
Bioprospecting Microalgae from Sewage Water: Assessment of Biochemicals for Biomass Utilization
01/12/2023 - Abstract Microalgal species from sewage treatment plant were identified by 18S rRNA sequencing and were explored for total lipids, carbohydrate, and protein contents, to serve as...
Immune Privileges as a Result of Mutual Regulation of Immune and Stem Systems
01/12/2023 - Abstract Immune privileges of cancer stem cells is a well-known and widely studied problem, as presence of such cells in tumors is associated with refractoriness, recurrence,...
Nrf2 activator Diethyl Maleate attenuates ROS mediated NLRP3 inflammasome activation in murine microglia
01/12/2023 - Abstract Microglia are the tissue-resident immune cells of the central nervous system. As a part of the innate immune response, NLR Family Pyrin Domain Containing Protein 3...
Fish cell line: depositories, web resources and future applications
01/12/2023 - Abstract Cell lines are important bioresources to study the key biological processes in the areas like virology, pathology, immunology, toxicology, biotechnology, endocrinology...
TRIM32 Inhibits NEK7 Ubiquitylation-Dependent Microglia Pyroptosis After Spinal Cord Injury
01/12/2023 - Abstract Spinal cord injury (SCI) is a disabling disease associated with microglial activation. Tripartite motif containing 32 (TRIM32) is an E3 ubiquitin ligase that plays a role...
LINC02532 by Mediating miR-541-3p/HMGA1 Axis Exerts a Tumor Promoter in Breast cancer
01/12/2023 - Abstract The newly discovered LINC02532 is abnormally expressed in a variety of cancers and promotes cancer progression. The research proposed to discover the biological and...
Encapsulated stem cell–derived ? cells exert glucose control in patients with type 1 diabetes
01/12/2023 - Nature Biotechnology, Published online: 27 November 2023; doi:10.1038/s41587-023-02055-5? cells derived from...
Custom-made meniscus biofabrication
01/12/2023 - Iron oxide (see Glossary) nanoparticles (FeONPs), mainly represented by magnetite (Fe3O4), maghemite (?-Fe2O3), and mixed ferrites, are part of the ferrimagnetic and ferromagnetic classes of magnetic...
Spatial -omics technologies: the new enterprise in 3D breast cancer models
01/12/2023 - Engineered antibodies are essential tools for research and advanced pharmacy. In the development of therapeutics, antibodies are excellent candidates as they offer both target recognition and...
Fighting the battle against evolution: designing genetically modified organisms for evolutionary stability
01/12/2023 - PG (Box 1) integrates genomic and transcriptomic data to help identify novel peptides from mass spectrometry (MS) (see Glossary) based proteomic data; in turn, the proteomic data can be used to...
Enhancing CRISPR/Cas systems with nanotechnology
01/12/2023 - The impact of next-generation sequencing (NGS) cannot be overestimated. The technology has transformed the field of life science, contributing to a dramatic expansion in our understanding of human...
Inhibition of PI3K/Akt/mTOR Signaling Pathway Suppresses 5-Fluorouracil Resistance in Gastric Cancer
28/11/2023 - Abstract Background At present, 5-Fluorouracil (5-FU) is a crucial anti-cancer drug and is widely used for the treatment of various...
Therapeutic effects and potential mechanisms of endoscopic submucosal injection of mesenchymal stem cells on chronic atrophic gastritis
28/11/2023 - Scientific Reports, Published online: 25 November 2023; doi:10.1038/s41598-023-48088-3Therapeutic effects and...
Effects of wasp (Vespa crabro) nest extracts on virus replication of Autographa californica nuclear polyhedrosis virus on Spodoptera frugiperda cell culture
28/11/2023 - Abstract The antiviral properties of the extracts of Vespa crabro nests collected from the Black Sea, Turkey have been investigated on Spodoptera frugiperda (Sf) cell cultures of...
Evaluation of the PrimeFlow RNA assay as a method of detection of SARS-CoV-2 single and dual Infections
28/11/2023 - Abstract Given the implications of increased transmissibility, virulence, host range, and immune escapes of emerging variants of SARS-CoV-2, developing in vitro models that allow...
Insights into the Potential Role of Plasmids in the Versatility of the Genus Pantoea
28/11/2023 - Abstract In the past two decades, 25 different species of the genus Pantoea within the Enterobacteriaceae family, have been isolated from different environmental niches. These...
Immunogenicity and Protective Efficacy of Nucleic Acid-Based Vaccines Against COVID-19: A Systematic Review
28/11/2023 - Abstract To overcome the COVID-19 pandemic, the development of safe and effective vaccines is crucial. With the enormous information available on vaccine development for COVID-19,...