Biotecnología
Biotecnología
Evaluation of point-of-care multiplex polymerase chain reaction in guiding antibiotic treatment of patients acutely admitted with suspected community-acquired pneumonia in Denmark: A multicentre randomised controlled trial
01/12/2023 -
Background Rapid and accurate detection of pathogens is needed in community-acquired pneumonia (CAP) to enable appropriate antibiotics and to slow the development of antibiotic resistance. We...
Attitudes and practices on antibiotic use and its emerging threats among Lebanese dairy veterinarians: a case study from a developing country
01/12/2023 -
IntroductionThis study aimed to explore how veterinarians (vets) rationalized their prescribing decisions for antimicrobial (AM) uses, the barriers they perceived to implement proper farm...
Characterization of a mobilizable megaplasmid carrying multiple resistance genes from a clinical isolate of Pseudomonas aeruginosa
28/11/2023 -
IntroductionThe horizontal transfer of antibiotic resistance genes mediated by plasmids seriously hinders the effectiveness of modern medical treatment, and thus has attracted widespread...
Decolonization of asymptomatic carriage of multi-drug resistant bacteria by bacteriophages?
24/11/2023 -
Antimicrobial resistance is a major threat to human and animal health and accounted for up to 4.5 million deaths worldwide in 2019. Asymptomatic colonization of the digestive tract by multidrug...
Porin-independent accumulation in Pseudomonas enables antibiotic discovery
24/11/2023 -
Nature, Published online: 22 November 2023; doi:10.1038/s41586-023-06763-5Imaging of quantum oscillations in...
Author Correction: Delivery mode and perinatal antibiotics influence the predicted metabolic pathways of the gut microbiome
24/11/2023 -
Scientific Reports, Published online: 23 November 2023; doi:10.1038/s41598-023-47520-yAuthor Correction:...
Burden of diarrhea and antibiotic use among children in low-resource settings preventable by <i>Shigella</i> vaccination: A simulation study
24/11/2023 -
Background Shigella is a leading cause of diarrhea and dysentery in children in low-resource settings, which is frequently treated with antibiotics. The primary goal of a Shigella...
Storage of boar semen at 17°C without conventional antibiotics in an extender containing an organic bactericidal substance
22/11/2023 -
IntroductionFacing the global threat of antimicrobial resistance, the reduction of antibiotic use in semen extenders is a main goal in artificial insemination (AI) of pigs. The aim of this study...
Antibiotic nanoparticles boost antitumor immunity
17/11/2023 -
Nature Biotechnology, Published online: 16 November 2023; doi:10.1038/s41587-023-02046-6Liposomes loaded with...
Composition, antibiotic resistance, and virulence analysis of microbiota in dormitory drain pipes
15/11/2023 -
IntroductionDormitory washbasins can breed microorganisms that produce odorous gases, polluting the indoor environment.MethodsWe utilized metagenome sequencing to analyze the microbiota of...
Nonsense mutation suppression is enhanced by targeting different stages of the protein synthesis process
15/11/2023 -
The introduction of premature termination codons (PTCs), as a result of splicing defects, insertions, deletions, or point mutations (also termed nonsense mutations), lead to numerous genetic...
Profiling toxin genes and antibiotic resistance in Bacillus cereus isolated from pre-launch spacecraft
15/11/2023 -
Characterization of the microbiomes of pre-launch spacecraft in spacecraft assembly facilities is an important step in keeping crews healthy during journeys that can last several hundred days in...
Host cell-based screening assays for identification of molecules targeting Pseudomonas aeruginosa cyclic di-GMP signaling and biofilm formation
15/11/2023 -
The rapid emergence of bacterial resistance to antibiotics in current use is occurring worldwide and poses a significant threat to global healthcare systems. Recent research to identify new...
Superior Performance of Iron-Coated Silver Nanoparticles and Cefoxitin as an Antibiotic Composite Against Methicillin-Resistant Staphylococcus aureus (MRSA): A Population Study
15/11/2023 -
Abstract The synergistic effects of antimicrobial nanostructures with antibiotics present a promising solution for overcoming resistance in methicillin-resistant Staphylococcus...
Combating Antibiotic Resistance
09/11/2023 -
Misuse and overuse of antibiotics have contributed to antibiotic resistance, a phenomenon that reduces or eliminates the effectiveness of antibiotics
pts promoter influences antibiotic resistance via proton motive force and ROS in Escherichia coli
07/11/2023 -
IntroductionGlucose level is related to antibiotic resistance. However, underlying mechanisms are largely unknown.MethodsSince glucose transport is performed by phosphotransferase system...
The absence of surface D-alanylation, localized on lipoteichoic acid, impacts the Clostridioides difficile way of life and antibiotic resistance
30/10/2023 -
IntroductionThe dlt operon encodes proteins responsible for the esterification of positively charged D-alanine on the wall teichoic acids and lipoteichoic acids of Gram-positive bacteria. This...
Alkyl gallates inhibit serine O-acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics
27/10/2023 -
A principal concept in developing antibacterial agents with selective toxicity is blocking metabolic pathways that are critical for bacterial growth but that mammalian cells lack. Serine...
Efficacy of Raphamin against Pneumococcal Infection: a Preclinical Study
23/10/2023 -
The aim of the study was to evaluate the activity of Raphamin in a model of non-lethal pneumococcal infection caused by Streptococcus pneumoniae 3 in BALB/c mice. The drug or placebo was...
The impact of antibiotic prophylaxis with intracameral cefuroxime on postoperative infectious endophthalmitis rates in a high-volume cataract surgery center
23/10/2023 -
Scientific Reports, Published online: 21 October 2023; doi:10.1038/s41598-023-45398-4The impact of antibiotic...
