Biotecnología

Biotecnología

Harnessing microRNA-enriched extracellular vesicles for liquid biopsy
26/02/2024 - Extracellular microRNAs (miRNAs) can be detected in body fluids and hold great potential as cancer biomarkers. Extracellular miRNAs are protected from degradation by binding various proteins and...
Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase
26/02/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 8, February 2024.
Exploration of the protective mechanisms of Icariin against cisplatin-induced renal cell damage in canines
26/02/2024 - This study delves into the protective mechanisms of Icariin (ICA) against cisplatin-induced damage in Madin-Darby canine kidney (MDCK) cells. Comprising two distinct phases, the investigation...
KAT8-catalyzed lactylation promotes eEF1A2-mediated protein synthesis and colorectal carcinogenesis
26/02/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 8, February 2024.
Squid meal and shrimp hydrolysate as novel protein sources for dog food
26/02/2024 - The world’s growing pet population is raising sustainability and environmental concerns for the petfood industry. Protein-rich marine by-products might contribute to mitigating negative...
Heterogeneous osteoimmune profiles via single-cell transcriptomics in osteoporotic patients who fail bisphosphonate treatment
26/02/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 8, February 2024.
Structural and Functional Characterization of Obesumbacterium proteus Phytase: A Comprehensive In-Silico Study
26/02/2024 - Abstract Phytate, also known as myoinositol hexakisphosphate, exhibits anti-nutritional properties and possesses a negative environmental impact. Phytase enzymes break down...
Circular RNAs from linear viral RNA genomes: A distinct dimension in the virus world
26/02/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 8, February 2024.
Hyperbaric Oxygen Upregulates Mst1 to Activate Keap1/Nrf2/HO-1 Pathway Resisting Oxidative Stress in a Rat Model of Acute Myocardial Infarction
26/02/2024 - Abstract This study aimed to investigate the protective effects and mechanisms of hyperbaric oxygen (HBO) preconditioning in a rat model of acute myocardial infarction (MI)...
Catechol- and thiol-containing binder that aggregates granular xenografts in reconstructed bone defects by mimicking mussel wet adhesion
26/02/2024 - Abstract Xenograft bone granules are bone graft materials that are widely used to reconstruct bone tissue in clinical practice, and their clinical success requires aggregation...
MicroRNAs Associated with Keloids Identified by Microarray Analysis and In Vitro Experiments
26/02/2024 - Abstract MicroRNAs (miRNAs) play a crucial role in gene regulation and the development of keloid. This research aimed to identify and verify miRNAs associated with keloids by...
Targeted siRNA delivery to lung epithelia reduces airway inflammation in a mouse model of allergic asthma
26/02/2024 - Abstract Asthma is a chronic inflammatory disease triggered by allergic reactions in the bronchia. These reactions lead to swelling of mucous membranes, hypersecretion of mucus,...
Super-additive cooperation
26/02/2024 - Nature, Published online: 21 February 2024; doi:10.1038/s41586-024-07089-6Studies using genetic screening,...
Development and optimization of a modular two-fragment LacI switch for enhanced biosensor applications
26/02/2024 - Abstract Being able to perform modular design of artificial transcription factors is useful in bioengineering and synthetic biology, particularly in the development of biosensors...
The life and gruesome death of a bog man revealed after 5,000 years
26/02/2024 - Nature, Published online: 21 February 2024; doi:10.1038/d41586-024-00520-yMassive environmental DNA project...
Vibrio species as next-generation chassis for accelerated synthetic biology
26/02/2024 - Abstract Synthetic biology aims to establish engineering principles for biological systems by leveraging the design-build-test-learn (DBTL) cycle. Central to the success of the...
Daily briefing: Great ‘Stone Age’ wall discovered in Baltic Sea
26/02/2024 - Nature, Published online: 21 February 2024; doi:10.1038/d41586-024-00511-zA system that edits RNA rather than...
Combining metabolic flux analysis with proteomics to shed light on the metabolic flexibility: the case of Desulfovibrio vulgaris Hildenborough
26/02/2024 - IntroductionDesulfovibrio vulgaris Hildenborough is a gram-negative anaerobic bacterium belonging to the sulfate-reducing bacteria that exhibits highly versatile metabolism. By switching from one...
A deep learning-based method for modeling of RNA structures from cryo-EM maps
26/02/2024 - Nature Biotechnology, Published online: 23 February 2024; doi:10.1038/s41587-024-02162-xWe developed a deep...
Electroacupuncture at ST25 corrected gut microbial dysbiosis and SNpc lipid peroxidation in Parkinson’s disease rats
26/02/2024 - IntroductionParkinson’s disease (PD) remains one kind of a complex, progressive neurodegenerative disease. Levodopa and dopamine agonists as widely utilized PD therapeutics have not shown...
OMArk, a tool for gene annotation quality control, reveals erroneous gene inference
26/02/2024 - Nature Biotechnology, Published online: 21 February 2024; doi:10.1038/s41587-024-02155-wWe developed the OMArk...