Biotecnología

Biotecnología

Identification of new potent NLRP3 inhibitors by multi-level in-silico approaches
22/04/2024 - Nod-like receptor protein 3 (NLRP-3), is an intracellular sensor that is involved in inflammasome activation, and the aberrant expression of NLRP3 is responsible for diabetes mellitus, its...
Analysis of the coupling coordination of livestock production, residential consumption, and resource and environmental carrying capacity in China
22/04/2024 - Increasing demands for livestock products have stimulated rapid increases in the number of livestock and the scale of farming, thus increasing pressure on resources and the environment. Coordinating...
WTAP-mediated N6-methyladenine Modification of circEEF2 Promotes Lung Adenocarcinoma Tumorigenesis by Stabilizing CANT1 in an IGF2BP2-dependent Manner
22/04/2024 - Abstract N6-methyladenosine (m6A) is a common posttranscriptional RNA modification and plays an important role in cancer biology. Circular RNAs (circRNAs) are also reported to...
Ion transport in muscle acetylcholine receptor maintained by conserved salt bridges between the pore and lipid membrane
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Episymbiotic Saccharibacteria TM7x modulates the susceptibility of its host bacteria to phage infection and promotes their coexistence
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Pharmacological expansion of type 2 alveolar epithelial cells promotes regenerative lower airway repair
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Genetic mechanism regulating diversity in the placement of eyes on the head of animals
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Synthesis, characterization, and antibacterial activity studies of two Co(II) complexes with 2-[(E)-(3-acetyl-4-hydroxyphenyl)diazenyl]-4-(2-hydroxyphenyl)thiophene-3-carboxylic acid as a ligand
22/04/2024 - Two new Cobalt(II) complexes 12 and 13 have been synthesized from 2-[(E)-(3-acetyl-4-hydroxyphenyl)diazenyl]-4-(2-hydroxyphenyl)thiophene-3-carboxylic acid (11) as a novel ligand. These three new...
Metals levels and human health risk assessment in eight commercial fish species collected from a market, Wuhan, China
22/04/2024 - IntroductionHeavy metals are ubiquitous environmental pollutants, and fish could be contaminated by these metals, potentially posing a threat to human health through the food chain. Understanding the...
Exploring the Role of Ferroptosis-Related Circular RNAs in Subarachnoid Hemorrhage
22/04/2024 - Abstract Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular event associated with high mortality and significant morbidity. Recent studies have highlighted the...
Hepatocyte regeneration is driven by embryo-like DNA methylation reprogramming
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
A conserved strategy to attack collagen: The activator domain in bacterial collagenases unwinds triple-helical collagen
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Modern archaeological research and the importance of information management
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Development of a stability indicating high-performance liquid chromatography method for determination of cenobamate: study of basic degradation kinetics
22/04/2024 - This study presents a stability indicating high-performance liquid chromatography HPLC method for the determination of cenobamate (CNB) in presence of its main impurity (CNB H-impurity) and...
Neural crest origin of sympathetic neurons at the dawn of vertebrates
22/04/2024 - Nature, Published online: 17 April 2024; doi:10.1038/s41586-024-07316-0Human genetic evidence increases the...
Developmental trajectories of GABAergic cortical interneurons are sequentially modulated by dynamic FoxG1 expression levels
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Molecular mechanism underlying SNARE-mediated membrane fusion enlightened by all-atom molecular dynamics simulations
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Harmonic resonance and entrainment of propagating chemical waves by external mechanical stimulation in BZ self-oscillating hydrogels
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Blink and you see it
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.