Biotecnología

Biotecnología

Probabilistic seismic multi-hazard loss estimation of Iran gas trunklines
21/05/2020 - The location of Iran in addition to holding the world's second-largest gas reserves, makes this country an important transporter of natural gas in the world. Moreover, Iran is a country that...
Analytical performance of thrombospondin-1 and cathepsin D immunoassays part of a novel CE-IVD marked test as an aid in the diagnosis of prostate cancer
21/05/2020 - The Prostate Specific Antigen (PSA) test suffers from low specificity for the diagnosis of Prostate Cancer (PCa). We originally discovered two cancer-related proteins thrombospondin-1 (THBS1) and...
Canine hip dysplasia screening: Comparison of early evaluation to final grading in 231 dogs with Fédération Cynologique Internationale A and B
21/05/2020 - Objectives This study aimed to verify if a significant difference exists between parameters in the early evaluation of normal and near-normal hip joints, to evaluate the influence of age and breed...
Live-cell protein engineering with an ultra-short split intein [Chemistry]
21/05/2020 - Sepsis is a life-threatening organ dysfunction condition caused by a dysregulated host response to an infection. Here we report that the circulating levels of growth and differentiation factor-15...
?-Synuclein Overexpression in SH-SY5Y Human Neuroblastoma Cells Leads to the Accumulation of Thioflavin S-positive Aggregates and Impairment of Glycolysis
21/05/2020 - Abstract Deterioration of energy metabolism in affected cells is an important feature of synucleinopathies, including Parkinson's disease. Here, we studied the association...
Restoration of estrous cycles by co-transplantation of mouse ovarian tissue with MSCs
21/05/2020 - Abstract This study investigates the effect of bone marrow (BM-MSCs) and visceral peritoneum (VP-MSCs)-derived mesenchymal stem cells on the transplanted ovary. VP-MSCs and...
How to Conduct a Bayesian Network Meta-Analysis
21/05/2020 - Network meta-analysis is a general approach to integrate the results of multiple studies in which multiple treatments are compared, often in a pairwise manner. In this tutorial, we illustrate the...
A <i>Lobularia maritima</i> LmSAP protein modulates gibberellic acid homeostasis via its A20 domain under abiotic stress conditions
21/05/2020 - Stress-associated proteins (SAPs) are favorable targets to improve stress tolerance in plants, owing to their roles in developmental processes and stress responses. However, the role of SAPs and the...
Concentrations of toxic metals and essential trace elements vary among individual neurons in the human locus ceruleus
21/05/2020 - Objective Damage to locus ceruleus neurons could play a part in the pathogenesis of neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis because...
Host nutrient milieu drives an essential role for aspartate biosynthesis during invasive Staphylococcus aureus infection [Microbiology]
21/05/2020 - Foxp3-expressing regulatory T cells (Tregs) can be generated in vitro by antigenic stimulation of conventional T cells (Tconvs) in the presence of TGF-? and IL-2. However, unlike Foxp3+ naturally...
Light-controlled twister ribozyme with single-molecule detection resolves RNA function in time and space [Chemistry]
21/05/2020 - Habituation is a form of simple memory that suppresses neural activity in response to repeated, neutral stimuli. This process is critical in helping organisms guide attention toward the most salient...
The sprint to solve coronavirus protein structures — and disarm them with drugs
21/05/2020 - Nature, Published online: 15 May 2020; doi:10.1038/d41586-020-01487-2Breakneck triage nails many diagnoses, but...
Leak release momentum and the convective flow influence on the calculation of flammable cloud
21/05/2020 - A mathematical model predicting the fluid flow dynamics of accidental clouds is introduced. It has been found that the dimensionless flammable cloud is related to the accidental leak rate, wind...
The perceived impact of isoniazid resistance on outcome of first-line rifampicin-throughout regimens is largely due to missed rifampicin resistance
21/05/2020 - Background Meta-analyses on impact of isoniazid-resistant tuberculosis informed the World Health Organization recommendation of a levofloxacin-strengthened rifampicin-based regimen.We estimated...
Prevalence of anti-hepatitis E virus IgG antibodies in sera from hemodialysis patients in Tripoli, Lebanon
21/05/2020 - Hepatitis E virus (HEV) is an important global public health concern. Several studies reported a higher HEV prevalence in patients undergoing regular hemodialysis (HD). In Lebanon, the epidemiology...
Transcriptomic network analyses shed light on the regulation of cuticle development in maize leaves [Plant Biology]
21/05/2020 - Numerous genes whose mutations cause, or increase the risk of, Parkinson’s disease (PD) have been identified. An inactivating mutation (R258Q) in the Sac inositol phosphatase domain of synaptojanin...
Mechanisms of Acinetobacter baumannii Capsular Polysaccharide Cleavage by Phage Depolymerases
21/05/2020 - Abstract Aerobic gram-negative bacterium Acinetobacter baumannii has recently become one of the most relevant pathogens associated with hospital-acquired infections worldwide....
Morphological and phenotypical diversity of eosinophils in the rat ileum
21/05/2020 - Abstract Eosinophils are abundantly present in intestinal mucosa. However, the morphological characteristics of their cellular population are still largely unknown. In this study,...
At-line N-linked glycan profiling for monoclonal antibodies with advanced sample preparation and high-performance liquid chromatography
21/05/2020 - ription>https://www.sciencedirect.com/science/article/pii/S1389172320302036?dgcid=rss_sd_allhttps://www.sciencedirect.com/science/article/pii/S1389172320302036Simultaneous anammox and denitrification...