Biotecnología
Biotecnología
E3-ubiquitin ligase, FBXW7 regulates mitotic progression by targeting BubR1 for ubiquitin-mediated degradation
01/12/2023 -
Abstract Faithful chromosome segregation requires correct attachment of kinetochores with the spindle microtubules. Erroneously-attached kinetochores recruit proteins to...
Exosomes for CRISPR-Cas9 Delivery: The Cutting Edge in Genome Editing
01/12/2023 -
Abstract Gene mutation correction was challenging until the discovery of clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein (Cas)....
Exercise and aerobic capacity in individuals with spinal cord injury: A systematic review with meta-analysis and meta-regression
01/12/2023 -
Background A low level of cardiorespiratory fitness [CRF; defined as peak oxygen uptake (V?O2peak) or peak power output (PPO)] is a widely reported consequence of spinal cord injury (SCI) and a...
Trends and determinants of early initiation of breastfeeding in Indonesia: A multivariate decomposition analysis
01/12/2023 -
Background Early initiation of breastfeeding (EIBF) is key to reducing neonatal morbidity and mortality, however, little is known about the determinants of the trends of EIBF prevalence in...
Effects of microbes in pig farms on occupational exposed persons and the environment
01/12/2023 -
In terms of pig farming, pig gut microbes have a significant effect on farmers and the farm environment. However, it is still unclear which microbial composition is more likely to contribute to this...
Function of the Conserved Non-Functional Residues in Apomyoglobin – to Determine and to Preserve Correct Topology of the Protein
01/12/2023 -
Abstract In this paper the answer to O. B. Ptitsyn’s question “What is the role of conserved non-functional residues in apomyoglobin” is presented, which is based on...
Comparing the genetic typing methods for effective surveillance and rabies control in Georgia
01/12/2023 -
A full nucleoprotein gene sequencing of 68 isolates collected from passive rabies surveillance system in Georgia between 2015 and 2016 identified two distinct dog rabies phylogroups, GEO_V1 and...
Evaluation of in vitro intrinsic radiosensitivity and characterization of five canine high-grade glioma cell lines
01/12/2023 -
Glioma is the most common primary brain tumor in dogs and predominantly affects brachycephalic breeds. Diagnosis relies on CT or MRI imaging, and the proposed treatments include surgical...
CONIPHER: a computational framework for scalable phylogenetic reconstruction with error correction
01/12/2023 -
https://www.nature.com/articles/s41596-023-00913-9 Nature Protocols, Published online: 28 November 2023;
Environmental disclosure practices in mixed ownership models: A study of Chinese private enterprises
01/12/2023 -
Environmental information disclosure is critical avenue for stakeholders to gauge the fulfillment of corporate environmental responsibilities, as well as a key path for companies to gain social...
Limitations in predicting reduced susceptibility to third generation cephalosporins in <i>Escherichia coli</i> based on whole genome sequence data
01/12/2023 -
Prediction of antibiotic resistance from whole genome sequence (WGS) data has been proposed. However, the performance of WGS data analysis for this matter may be influenced by the resistance...
Adaptive DNA amplification of synthetic gene circuit opens a way to overcome cancer chemoresistance
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
Deletion of V?3+CD4+ T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8+ T cells
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
An acetyltranferase moonlights as a regulator of the RNA binding repertoire of the RNA chaperone Hfq in Escherichia coli
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
Melanopic metrics: Advancing the characterization of everyday light patterns
01/12/2023 -
Proceedings of the National Academy of Sciences, Volume 120, Issue 49, December 2023.
Interaction of sulfasalazine with outer surface of boron-nitride nanotube as a drug carrier in aqueous solution: insights from quantum mechanics and Monte Carlo simulation
01/12/2023 -
The improvement of the solubility of sulfasalazine in physiological media was the major aim of this study. Accordingly, BNNT inspected as a notable candidate for the carriage of this drug in aqueous...
Bioprospecting Microalgae from Sewage Water: Assessment of Biochemicals for Biomass Utilization
01/12/2023 -
Abstract Microalgal species from sewage treatment plant were identified by 18S rRNA sequencing and were explored for total lipids, carbohydrate, and protein contents, to serve as...
Clinical efficacy of inhaled corticosteroids in patients with coronavirus disease 2019: A living review and meta-analysis
01/12/2023 -
Inhaled corticosteroids are known to be relatively safe for long-term use in inflammatory respiratory diseases and it has been repurposed as one of the potential therapies for outpatients with...
Cell-Penetrating Peptides as Vehicles for Delivery of Therapeutic Nucleic Acids. Mechanisms and Application in Medicine
01/12/2023 -
Abstract Currently, nucleic acid therapeutics are actively developed for the treatment and prophylactic of metabolic disorders and oncological, inflammatory, and infectious...
Methods for Assessment of Nucleotide Excision Repair Efficiency
01/12/2023 -
Abstract Nucleotide excision repair (NER) is responsible for removing a wide variety of bulky adducts from DNA, thus contributing to the maintenance of genome stability. The...
