Biotecnología
Biotecnología
The Impact of Long-Term Hypoxia on the Antioxidant Defense System in the Siberian Frog Rana amurensis
16/04/2024 -
Abstract The Siberian frog Rana amurensis has a uniquely high tolerance to hypoxia among amphibians, as it is able to withstand several months underwater with almost no oxygen...
Bioengineered MSCCxcr2 transdifferentiated keratinocyte-like cell-derived organoid potentiates skin regeneration through ERK1/2 and STAT3 signaling in diabetic wound
16/04/2024 -
Abstract Skin regeneration is severely compromised in diabetic foot ulcers. Allogeneic mesenchymal stem cell (MSC) transplantation is limited due to the poor engraftment,...
Isolation and Characterization of Paracoccus maritimus sp. nov., from Intertidal Sediment
16/04/2024 -
Abstract A novel Paracoccus-related strain, designated YLB-12T, was isolated from a sediment sample from the tidal zone of Shapowei Port, Xiamen, Fujian Province, PR China. The...
Microbiome and lipidomic analysis reveal the interplay between skin bacteria and lipids in a cohort study
16/04/2024 -
Human skin acts as a protective barrier between the body and the external environment. Skin microbiome and intercellular lipids in the stratum corneum (SC) are essential for maintaining skin barrier...
Double-walled Al-based MOF with large microporous specific surface area for trace benzene adsorption
16/04/2024 -
Nature Communications, Published online: 13 April 2024; doi:10.1038/s41467-024-47615-8Maintaining a healthy...
Interpreting population- and family-based genome-wide association studies in the presence of confounding
16/04/2024 -
A central aim of genome-wide association studies (GWASs) is to estimate direct genetic effects: the causal effects on an individual’s phenotype of the alleles that they carry. However, estimates of...
The efficacy of ferroptosis-inducing compounds IKE and RSL3 correlates with the expression of ferroptotic pathway regulators CD71 and SLC7A11 in biliary tract cancer cells
16/04/2024 -
Introduction Biliary tract cancer (BTC) is a lethal disease with a bad overall survivability, partly arising from inadequate therapeutic alternatives, detection at a belated stage, and a...
Determinants of stillbirth among women who delivered in hospitals of North Wollo Zone, Northeast Ethiopia: A case-control study
16/04/2024 -
Background Stillbirth is a silent tragedy that shatters the lives of women, families, and nations. Though affecting over 2 million infants globally in 2019, it remains overlooked, with no specific...
Overexpression of the limk1 Gene in Drosophila melanogaster Can Lead to Suppression of Courtship Memory in Males
16/04/2024 -
Abstract Courtship suppression is a behavioral adaptation of the fruit fly. When majority of the females in a fly population are fertilized and non-receptive for mating, a...
PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGF? signaling
16/04/2024 -
Abstract Heterozygous mutations in any of three major genes, BRCA1, BRCA2 and PALB2, are associated with high-risk hereditary breast cancer susceptibility frequently seen as...
Antibacterial Property of Silver Nanoparticles Green Synthesized from Stachys schtschegleevii Plant Extract on Urinary Tract Infection Bacteria
16/04/2024 -
Abstract Urinary tract infections are one of the most common infections worldwide. Given the increasing antibiotic resistance, monitoring antibiotic sensitivity patterns is...
Development of a dual immunochromatographic test strip to detect E2 and Erns antibodies against classical swine fever
16/04/2024 -
BackgroundIt is essential to consider a practical antibody test to successfully implement marker vaccines and validate vaccination efficacy against classical swine fever virus (CSFV). The test should...
Accessible computing platforms democratize neuroimaging data analysis
16/04/2024 -
tifier>doi:10.1038/s41592-024-02238-1 Nature Methods, Published online: 2024-04-11; | doi:10.1038/s41592-024-02238-1 2024-04-11 Nature Methods ...
Realism and robustness require increased sample size when studying both sexes
16/04/2024 -
A recent article claimed that researchers need not increase the overall sample size for a study that includes both sexes. This Formal Comment points out that that study assumed two sexes to have the...
Specific nanoprobe design for MRI: Targeting laminin in the blood-brain barrier to follow alteration due to neuroinflammation
16/04/2024 -
Chronic neuroinflammation is characterized by increased blood-brain barrier (BBB) permeability, leading to molecular changes in the central nervous system that can be explored with biomarkers of...
MiR-132-3p suppresses peritoneal fibrosis induced by peritoneal dialysis via targeting TGF-<i>?</i>1/Smad2/3 signaling pathway
16/04/2024 -
Background Peritoneal fibrosis (PF) is the main complication of peritoneal dialysis (PD) and the most common cause of cessation from PD. There is still no effective therapeutic approach to reserve...
Investigation of Potential Effects of Some Indole Compounds on the Glutathione S-Transferase Enzyme
16/04/2024 -
Abstract Glutathione S-transferases (GSTs) belong to the superfamily of multifunctional detoxification isoenzymes with an important role in cellular signaling. They can...
A novel fatty acid analogue triggers CD36–GPR120 interaction and exerts anti-inflammatory action in endotoxemia
16/04/2024 -
Abstract Inflammation is a mediator of a number of chronic pathologies. We synthesized the diethyl (9Z,12Z)-octadeca-9,12-dien-1-ylphosphonate, called NKS3, which decreased...
Saccharopolyspora ipomoeae sp. nov., an Actinomycete Isolated from Sweet Potato Field Soils
16/04/2024 -
Abstract During the course of the isolation of actinobacteria from sweet potato field soils collected from Phra Nakhon Si Ayutthaya province of Thailand, strain TS4A08T was...
The effect of DNA-binding proteins on insertion sequence element transposition upstream of the bgl operon in Escherichia coli
16/04/2024 -
The bglGFB operon in Escherichia coli K-12 strain BW25113, encoding the proteins necessary for the uptake and metabolism of ?-glucosides, is normally not expressed. Insertion of either IS1 or IS5...
Protein language models using convolutions
16/04/2024 -
Nature Methods, Published online: 12 April 2024; doi:10.1038/s41592-024-02252-3Protein language models using...
