Biotecnología
Biotecnología
Advancing biofoundry development: strategies and challenges
23/07/2024 -
Abstract This study explores the development of biofoundries, emphasizing the integration of synthetic biology with artificial intelligence (AI) and robotics. It outlines critical...
Cell-free supernatant-assisted biogenic silver nanoparticles enhance the antibacterial efficacy of communicating bacterial pathogens
23/07/2024 -
Abstract The use of nanoparticles (NPs) as an alternative to the current generation of conventional antibiotics has exploded in the research community in recent years, as evidence...
Recent advancements in flavonoid production through engineering microbial systems
23/07/2024 -
Abstract Flavonoids are a class of polyphenolic compounds found in plants that offer extensive health benefits and have applications in the pharmaceutical, cosmetic, and food...
Production of chitosan from Aspergillus niger and quantitative evaluation of the process using adapted analytical tools
23/07/2024 -
Abstract The chitosan production process from fishery waste is already established in industrial scale, whereby fungal chitosan is produced in lower amounts. Since fungal chitosan...
Extraction of the outer membrane protein pertactin from Bordetella pertussis with urea for the production of acellular pertussis vaccine
23/07/2024 -
Abstract Pertactin (PRN), a non-fimbrial outer membrane protein of Bordetella pertussis, is the limiting component of the acellular pertussis vaccine because of its low...
Imaging without barriers | Science
13/05/2024 -
Low-field magnetic resonance imaging can be engineered for widespread point-of-care diagnostics
Resumen del año 2023 por Nature Methods
23/01/2024 -
tifier>doi:10.1038/s41592-023-02158-6 Nature Methods, Published online: 2024-01-11; | doi:10.1038/s41592-023-02158-6 2024-01-11 Nature Methods 10.1038/s41592-023-02158-6...
Contributing roles of mitochondrial dysfunction and hepatocyte apoptosis in liver diseases through oxidative stress, post-translational modifications, inflammation, and intestinal barrier dysfunction
19/01/2024 -
Abstract This review provides an update on recent findings from basic, translational, and clinical studies on the molecular mechanisms of mitochondrial dysfunction and apoptosis...
Imaging of brain barrier inflammation and brain fluid drainage in human neurological diseases
19/01/2024 -
Abstract The intricate relationship between the central nervous system (CNS) and the immune system plays a crucial role in the pathogenesis of various neurological diseases....
Mechano-regulation by clathrin pit-formation and passive cholesterol-dependent tubules during de-adhesion
19/01/2024 -
Abstract Adherent cells ensure membrane homeostasis during de-adhesion by various mechanisms, including endocytosis. Although mechano-chemical feedbacks involved in this process...
Lactic acid promotes nucleus pulposus cell senescence and corresponding intervertebral disc degeneration via interacting with Akt
19/01/2024 -
Abstract The accumulation of metabolites in the intervertebral disc is considered an important cause of intervertebral disc degeneration (IVDD). Lactic acid, which is a...
Multiple circulating forms of neprilysin detected with novel epitope-directed monoclonal antibodies
19/01/2024 -
Abstract Neprilysin (NEP) is an emerging biomarker for various diseases including heart failure (HF). However, major inter-assay inconsistency in the reported concentrations of...
Emerging roles of mitochondrial functions and epigenetic changes in the modulation of stem cell fate
19/01/2024 -
Abstract Mitochondria serve as essential organelles that play a key role in regulating stem cell fate. Mitochondrial dysfunction and stem cell exhaustion are two of the nine...
Secrets and lies of host–microbial interactions: MHC restriction and trans-regulation of T cell trafficking conceal the role of microbial agents on the edge between health and multifactorial/complex diseases
19/01/2024 -
Abstract Here we critically discuss data supporting the view that microbial agents (pathogens, pathobionts or commensals alike) play a relevant role in the pathogenesis of...
Tryptophanylation of insulin receptor by WARS attenuates insulin signaling
19/01/2024 -
Abstract Increased circulating amino acid levels have been linked to insulin resistance and development of type 2 diabetes (T2D), but the underlying mechanism remains largely...
CENPA knockdown restrains cell progression and tumor growth in breast cancer by reducing PLA2R1 promoter methylation and modulating PLA2R1/HHEX axis
19/01/2024 -
Abstract Background Breast cancer is a lethal malignancy affecting females worldwide. It has been reported that upregulated centromere...
Intracellular calcium links milk stasis to lysosome-dependent cell death during early mammary gland involution
19/01/2024 -
Abstract Involution of the mammary gland after lactation is a dramatic example of coordinated cell death. Weaning causes distension of the alveolar structures due to the...
Epigenetic repression of CHCHD2 enhances survival from single cell dissociation through attenuated Rho A kinase activity
19/01/2024 -
Abstract During in vitro culture, human pluripotent stem cells (hPSCs) often acquire survival advantages characterized by decreased susceptibility to mitochondrial cell death,...
Overexpressing lipid raft protein STOML2 modulates the tumor microenvironment via NF-?B signaling in colorectal cancer
19/01/2024 -
Abstract Colorectal cancer (CRC) is characterized by a complex tumor inflammatory microenvironment, while angiogenesis and immunosuppression frequently occur concomitantly....
G-quadruplex structural dynamics at MAPK12 promoter dictates transcriptional switch to determine stemness in breast cancer
19/01/2024 -
Abstract P38? (MAPK12) is predominantly expressed in triple negative breast cancer cells (TNBC) and induces stem cell (CSC) expansion resulting in decreased survival of the...
