Biotecnología

Biotecnología

Post-Translational Oxidative Modifications of Hemostasis Proteins: Structure, Function, and Regulation
11/03/2024 - Abstract Reactive oxygen species (ROS) are constantly generated in a living organism. An imbalance between the amount of generated reactive species in the body and their...
Utility of sustainable ratio derivative spectrophotometry for the concurrent assay of synergistic repurposed drugs for COVID-19 infections; Insilico pharmacokinetics proof
11/03/2024 - The cutting-edge combination of fluvoxamine (FVM) and ivermectin (IVM) has been presented as a proposed dosage form for the treatment of COVID-19 infections in early diagnosed patients. The main...
Phenolic compounds weaken the impact of drought on soil enzyme activity in global wetlands
11/03/2024 - Soil enzymes play a central role in carbon and nutrient cycling, and their activities can be affected by drought-induced oxygen exposure. However, a systematic global estimate of enzyme...
Automated workflow for characterization of bacteriocin production in natural producers Lactococcus lactis and Latilactobacillus sakei
11/03/2024 - Lactic acid bacteria are commonly used as protective starter cultures in food products. Among their beneficial effects is the production of ribosomally synthesized peptides termed bacteriocins that...
Bees and chimpanzees learn from others what they cannot learn alone
11/03/2024 - Nature, Published online: 06 March 2024; doi:10.1038/d41586-024-00696-3Wearing a mask, social distancing and...
An engineered bacterial symbiont allows noninvasive biosensing of the honey bee gut environment
11/03/2024 - The honey bee is a powerful model system to probe host–gut microbiota interactions, and an important pollinator species for natural ecosystems and for agriculture. While bacterial biosensors can...
DFT and molecular simulation validation of the binding activity of PDE? inhibitors for repression of oncogenic k-Ras
11/03/2024 - The development of effective drugs targeting the K-Ras oncogene product is a significant focus in anticancer drug development. Despite the lack of successful Ras signaling inhibitors, recent research...
Vaccination coverage against COVID-19 among rural population in Haryana, India: A cross-sectional study
11/03/2024 - Background Conducting a study in rural pre-dominant areas will help to understand the penetration of the vaccination campaign during the COVID-19 health crisis. This study aimed to investigate...
Multicomponent DNAzyme Nanomachines: Structure, Applications, and Prospects
11/03/2024 - Abstract Nucleic acids (NAs) are important components of living organisms responsible for the storage and transmission of hereditary information. They form complex structures...
Preparation and property analysis of antioxidant of carbazole derivatives
11/03/2024 - Carbazole derivatives can be used as antioxidants in the lubricating oil industry. The alkylation of carbazole with 2-chloro-2-methylpropane and 2-bromopropane catalyzed by anhydrous aluminum...
Identification of bacteria and fungi responsible for litter decomposition in desert steppes via combined DNA stable isotope probing
11/03/2024 - IntroductionSoil microorganisms play crucial roles in determining the fate of litter in desert steppes because their activities constitute a major component of the global carbon (C) cycle. Human...
O-sialoglycoprotein Endopeptidase (OSGEP) Suppresses Hepatic Ischemia-Reperfusion Injury-Induced Ferroptosis Through Modulating the MEK/ERK Signaling Pathway
11/03/2024 - Abstract Hepatic ischemia–reperfusion injury (HIRI) was widely accepted as a critical complication of liver resection and transplantation. A growing body of evidence suggested...
Near-cognate tRNAs increase the efficiency and precision of pseudouridine-mediated readthrough of premature termination codons
11/03/2024 - Nature Biotechnology, Published online: 06 March 2024; doi:10.1038/s41587-024-02165-8Disease-related premature...
Cross-frequency coupling in cortico-hippocampal networks supports the maintenance of sequential auditory information in short-term memory
11/03/2024 - It has been suggested that cross-frequency coupling in cortico-hippocampal networks enables the maintenance of multiple visuo-spatial items in working memory. However, whether this mechanism acts as...
The primary ciliary dyskinesia-related genetic risk score is associated with susceptibility to adult-onset asthma
11/03/2024 - Background Disturbance of mucociliary clearance is an important factor in the pathogenesis of asthma. We hypothesized that common variants in genes responsible for ciliary function may contribute...
Sampling of healthcare professionals’ perspective on point-of-care technologies from 2019–2021: A survey of benefits, concerns, and development
11/03/2024 - Point-of-care technology (POCT) plays a vital role in modern healthcare by providing a fast diagnosis, improving patient management, and extending healthcare access to remote and resource-limited...
Formation of Supplementary Metal-Binding Centers in Proteins under Stress Conditions
11/03/2024 - Abstract In many proteins, supplementary metal-binding centers appear under stress conditions. They are known as aberrant or atypical sites. Physico-chemical properties of...
Voltammetric analysis of pholcodine on graphene-modified GNPs/PTs with green assessment
11/03/2024 - Pholcodine, an anti-tussive medication widely used as an over-the-counter, OTC drug, has recently faced restrictions in several countries. This paper presents a sensitive electrochemical approach for...
Characteristics of intestinal microbiota in preterm infants and the effects of probiotic supplementation on the microbiota
11/03/2024 - ObjectiveIn this study, we investigated the characteristics of the intestinal microbiota of preterm infants, and then analyzed the effects of probiotics supplementation on intestinal microbiota in...
Association Between Altered Microbiota Composition and Immune System-Related Genes in COVID-19 Infection
11/03/2024 - Abstract Microbiota and immunity affect the host's susceptibility to SARS-CoV-2 infection and the severity of COVID-19. This study aimed to identify significant alterations in...
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
11/03/2024 - Nature Biotechnology, Published online: 08 March 2024; doi:10.1038/s41587-024-02143-0An AI-generated...