Biotecnología
Biotecnología
Explorando el proteoma
08/07/2025 -
El artículo destaca el papel central de la proteómica química en aportar rigor al descubrimiento de fármacos covalentes, evidenciando su evolución hacia...
Comparación de modelos de cocultivo de células eucariotas con bacterias patógenas y/o comensales para ingeniería de tejidos
08/07/2025 -
Las infecciones en implantes médicos son una preocupación mayor. La revisión destaca modelos de cocultivo in vitro que integran células eucariotas y bacterias,...
Avances en biorreactores miniaturizados: conectando biotecnología e ingeniería de tejidos para mejorar el desarrollo de fármacos
08/07/2025 -
Este artículo revisa los avances recientes en biorreactores a microescala, resaltando sus diseños estructurales, limitaciones y potenciales aplicaciones. Se destacan configuraciones...
Beneficios y mecanismos moleculares de la baja temperatura en producción de proteínas recombinantes.
30/06/2025 -
La revisión explora cómo la hipotermia moderada (30–35?°C) incrementa la viabilidad y productividad de proteínas recombinantes en cultivos celulares de...
Desbloqueando el potencial de los microbios fluorescentes: explorando sus aplicaciones ecológicas e industriales
30/06/2025 -
El artículo revisa los microbios fluorescentes (arqueas, bacterias) destacando su diversidad, distribución y pigmentos responsables de fluorescencia. Se analizan sus aplicaciones en...
A solution to the postantibiotic era: phages as precision medicine
04/06/2025 -
Antibiotic-resistant bacterial infections pose a significant global health challenge. Phage therapy provides a promising alternative to antibiotics that enables the specific targeting of pathogenic...
Bioprinting
19/05/2025 -
El artículo presenta una composición y un proceso para la producción de un hidrogel ultrasólido, biocompatible, electroconductivo y elástico, destinado a...
World’s first personalized CRISPR therapy given to baby with genetic disease
19/05/2025 -
Un bebé llamado KJ Muldoon, de casi diez meses, es el primer ser humano conocido en recibir una terapia personalizada con CRISPR diseñada específicamente para corregir una...
Cryopreserving 3D cell culture models of Alzheimer’s disease in hydrogel microbeads
22/04/2025 -
El artículo analiza la importancia de superar los desafíos técnicos y de infraestructura para el cultivo anaeróbico de microorganismos, esenciales en muchos...
Re-imagining human cell culture media: Challenges, innovations, and future directions
31/03/2025 -
Filamentous fungi are essential industrial microorganisms that can serve as sources of enzymes, organic acids, terpenoids, and other bioactive compounds with significant applications in food,...
Recent advances in the application of CRISPR/Cas-based gene editing technology in Filamentous Fungi
26/03/2025 -
Brassinosteroids (BRs) are steroid phytohormones which regulate various developmental and physiological processes throughout plant life cycle, from seed development and germination, up to modulation...
Recent advances in CRISPR-Cas system for Saccharomyces cerevisiae engineering
26/03/2025 -
Terpenoids, also known as isoprenoids, represent the largest and most structurally diverse family of natural products, and their biosynthesis is closely related to cytochrome P450 enzymes (P450s)....
Fabrication of multifunctional hydrogels based on tannic acid-coated nanocrystalline cellulose
28/02/2025 -
Abstract Composite hydrogels are promising for wound healing, but combining strong antimicrobial properties with mechanical performance remains challenging due to potential...
Construcción y rediseño iterativo de synXVI, un cromosoma sintético de Saccharomyces cerevisiae de 903 kb.
18/02/2025 -
Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome
El consorcio global Sc2.0, creado en 2006, se dedica a...
Animal origins free products in cell culture media: a new frontier
17/01/2025 -
Abstract Despite the importance of finding replacements for fetal bovine serum (FBS), very few studies have focused on this subject. Historically, the use of animals and their...
Development of high-performance inducible and secretory expression vector and host system for enhanced recombinant protein production
15/01/2025 -
https://www.nature.com/articles/s41598-024-81001-0
Serum?free medium for recombinant protein expression in insect cells
08/01/2025 -
Cancer is a global health problem despite the most developed therapeutic modalities. The delivery of specific therapeutic agents to a target increases the effectiveness of cancer treatment by...
Novel buffer for long-term preservation of DNA in biological material at room temperature
13/11/2024 -
Science is in the midst of a reproducibility crisis and the integration of artificial intelligence into scientific research has only compounded the problem; yet could the technology hold the solution...
Integrated bioprocessing and genetic strategies to enhance soluble expression of anti-HER2 immunotoxin in E. Coli
13/11/2024 -
Immunotoxins are widely applied for cancer therapy. However, bacterial expression of immunotoxins usually leads to the formation of insoluble and non-functional recombinant proteins. This study was...
Hydrogel biomaterials that stiffen and soften on demand reveal that skeletal muscle stem cells harbor a mechanical memory
13/09/2024 -
Proceedings of the National Academy of Sciences, Volume 121, Issue 35, August 2024.
A 3D bioprinted antibacterial hydrogel dressing of gelatin/sodium alginate loaded with ciprofloxacin hydrochloride
10/09/2024 -
Graphical Abstract and Lay SummaryThis study aimed to identify fibroblast growth factor?2 (FGF?2)?derived peptides that enhance the proliferation of skeletal muscle satellite cells (SCs). Using a...
