Biotecnología

Biotecnología

Genetic insights into gut microbiota and risk of prostatitis: a Mendelian randomization study
16/04/2024 - BackgroundThe dysbiosis of gut microbiota (GM) is considered a contributing factor to prostatitis, yet the causality remains incompletely understood.MethodsThe genome-wide association study (GWAS)...
Deorphanizing solute carriers in Saccharomyces cerevisiae for secondary uptake of xenobiotic compounds
16/04/2024 - The exchange of small molecules between the cell and the environment happens through transporter proteins. Besides nutrients and native metabolic products, xenobiotic molecules are also transported,...
Enhanced resistance to heat and fungal infection in transgenic Trichoderma via over-expressing the HSP70 gene
16/04/2024 - Heat stress is one of the major abiotic stresses affecting the growth, sporulation, colonization and survival of Trichoderma viride. This study aimed to gain a better insight into the underlying...
Development of a dual immunochromatographic test strip to detect E2 and Erns antibodies against classical swine fever
16/04/2024 - BackgroundIt is essential to consider a practical antibody test to successfully implement marker vaccines and validate vaccination efficacy against classical swine fever virus (CSFV). The test should...
The Mechanism of Inhibition of Mycobacterial (p)ppGpp Synthetases by a Synthetic Analog of Erogorgiaene
16/04/2024 - Abstract The synthesis of (p)ppGpp alarmones plays a vital role in the regulation of metabolism suppression, growth rate control, virulence, bacterial persistence, and biofilm...
The effect of DNA-binding proteins on insertion sequence element transposition upstream of the bgl operon in Escherichia coli
16/04/2024 - The bglGFB operon in Escherichia coli K-12 strain BW25113, encoding the proteins necessary for the uptake and metabolism of ?-glucosides, is normally not expressed. Insertion of either IS1 or IS5...
Role of I182, R187, and K188 Amino Acid Residues in the Catalytic Domain of HIV-1 Integrase in the Processes of Reverse Transcription and Integration
16/04/2024 - Abstract Structural organization of HIV-1 integrase is based on a tetramer formed by two protein dimers. Within this tetramer, the catalytic domain of one subunit of the first...
Transcriptomic analysis identifies the shared diagnostic biomarkers and immune relationship between Atherosclerosis and abdominal aortic aneurysm based on fatty acid metabolism gene set
16/04/2024 - Background:Epidemiological research has demonstrated that there is a connection between lipid metabolism disorder and an increased risk of developing arteriosclerosis (AS) and abdominal aortic...
Oxidative Stress-Induced Platelet Apoptosis/Activation: Alleviation by Purified Curcumin via ASK1-JNK/p-38 Pathway
16/04/2024 - Abstract Platelets are known for their indispensable role in hemostasis and thrombosis. However, alteration in platelet function due to oxidative stress is known to mediate...
Identification of mulberry leaf flavonoids and evaluating their protective effects on H2O2-induced oxidative damage in equine skeletal muscle satellite cells
16/04/2024 - Introduction: Horses are susceptible to oxidative stress during strenuous endurance exercise, leading to muscle fatigue and damage. Mulberry leaf flavonoids (MLFs) possess significant antioxidant...
Protective Activity of Inactivated Rabies Vaccine Using Flagellin-Based Adjuvant
16/04/2024 - Abstract Rabies is a zoonotic disease with high lethality. Most human deaths are associated with the bites received from dogs and cats. Vaccination is the most effective...
Algae as an alternative source of protein in poultry diets for sustainable production and disease resistance: present status and future considerations
16/04/2024 - Integrating algae into poultry diets offers a promising avenue for enhancing nutrition, boosting sustainability efforts, and potentially stimulating disease resistance. This comprehensive review...
Role of the Gut Microbiome and Bacterial Amyloids in the Development of Synucleinopathies
16/04/2024 - Abstract Less than ten years ago, evidence began to accumulate about association between the changes in the composition of gut microbiota and development of human...
Integrative analysis of proteomics and lipidomic profiles reveal the fat deposition and meat quality in Duroc × Guangdong small spotted pig
16/04/2024 - IntroductionThis study aims to explore the important factors affecting the characteristics of different parts of pork.MethodsLipidomics and proteomics methods were used to analyze DAL (differential...
A continuum model for the elongation and orientation of Von Willebrand factor with applications in arterial flow
16/04/2024 - Abstract The blood protein Von Willebrand factor (VWF) is critical in facilitating arterial thrombosis. At pathologically high shear rates, the protein unfolds and binds to the...
Force-controlled release of small molecules with a rotaxane actuator
16/04/2024 - Nature, Published online: 10 April 2024; doi:10.1038/s41586-024-07291-6The effects of sex and androgens on the...
Antibacterial Property of Silver Nanoparticles Green Synthesized from Stachys schtschegleevii Plant Extract on Urinary Tract Infection Bacteria
16/04/2024 - Abstract Urinary tract infections are one of the most common infections worldwide. Given the increasing antibiotic resistance, monitoring antibiotic sensitivity patterns is...
Publisher Correction: Decoding chromatin states by proteomic profiling of nucleosome readers
16/04/2024 - Nature, Published online: 09 April 2024; doi:10.1038/s41586-024-07333-zAuthor Correction: Landscape-scale...
Microgreens and novel non-thermal seed germination techniques for sustainable food systems: a review
16/04/2024 - Abstract There are a number of cutting-edge techniques implemented in the germination process, including high pressure processing, ultrasonic, ultraviolet, light, non-thermal...
Double-walled Al-based MOF with large microporous specific surface area for trace benzene adsorption
16/04/2024 - Nature Communications, Published online: 13 April 2024; doi:10.1038/s41467-024-47615-8Maintaining a healthy...
Metformin Inhibits Zika Virus Infection in Trophoblast Cell Line
16/04/2024 - Abstract Zika virus (ZIKV) infections have been associated with severe clinical outcomes, which may include neurological manifestations, especially in newborns with intrauterine...