Biotecnología
Biotecnología
Reconstitution of Calcium Channel Protein Orai3 into Liposomes for Functional Studies
27/09/2023 -
Abstract Store-operated calcium entry (SOCE) is the main mechanism for the Ca2+ influx in non-excitable cells. The two major components of SOCE are stromal interaction...
NKD2 Trigger NF-?B Signaling Pathway and Facilitates Thyroid Cancer Cell Proliferation
27/09/2023 -
Abstract NKD inhibitor of WNT signaling pathway 2 (NKD2) is an emerging player in cancer onset and progression. Here, it was confirmed that THCA patients have robustly expressed...
Development of a sustainable multianalyte MEKC method for quantitation of the antihyperlipidemic drugs ezetimibe together with three statins. Greenness and whiteness appraisal studies
27/09/2023 -
Implementing powerful and sustainable research that complies with green analytical chemistry (GAC) and white analytical chemistry (WAC) fundamentals can downsize the environmental compliance costs...
Examination of critical factors influencing ruminant disease dynamics in the Black Sea Basin
27/09/2023 -
IntroductionRuminant production in the Black Sea basin (BSB) is critical for national economies and the subsistence of rural populations. Yet, zoonoses and transboundary animal diseases (TADs) are...
Integrating multimodal and multiscale connectivity blueprints of the human cerebral cortex in health and disease
27/09/2023 -
The brain is composed of disparate neural populations that communicate and interact with one another. Although fiber bundles, similarities in molecular architecture, and synchronized neural activity...
Heterologous Expression of Recombinant Proteins and Their Derivatives Used as Carriers for Conjugate Vaccines
27/09/2023 -
Abstract Carrier proteins that provide an effective and long-term immune response to weak antigens has become a real breakthrough in the disease prevention, making it...
Hsa_circ_0137652 Regulates miR-1205/CCNB1 Axis to Accelerate the Malignancy of Breast Cancer
27/09/2023 -
Abstract CircRNAs have become a hotspot in tumor research owing to their high stability and specific functions. We investigated the function of hsa_circ_0137652 in the onset and...
Higher sensitive selective spectrofluorometric determination of ritonavir in the presence of nirmatrelvir: application to new FDA approved co-packaged COVID-19 pharmaceutical dosage and spiked human plasma
27/09/2023 -
Ritonavir was recently combined with nirmatrelvir in a new approved co-packaged medication form for the treatment of COVID-19. Quantitative analysis based on fluorescence spectroscopy measurement was...
Influence on Accumulation Levels and Subcellular Localization of Prolamins by Fusion with the Functional Peptide in Transgenic Rice Seeds
27/09/2023 -
Abstract To exploit the rice seed-based oral vaccine against Sjögren’s syndrome, altered peptide ligand of N-terminal 1 (N1-APL7) from its M3 muscarinic acetylcholine...
ADAR-mediated regulation of PQM-1 expression in neurons impacts gene expression throughout <i>C</i>. <i>elegans</i> and regulates survival from hypoxia
27/09/2023 -
The ability to alter gene expression programs in response to changes in environmental conditions is central to the ability of an organism to thrive. For most organisms, the nervous system serves as...
Recent Developments in Bioprocessing of Recombinant Antibody Fragments
27/09/2023 -
Abstract Biotechnological and biomedical applications of antibodies have been on a steady rise since the 1980s. As unique and highly specific bioreagents, monoclonal...
miR-26b Targets CEP135 Gene to Regulate Nasopharyngeal Carcinoma Proliferation and Migration by NF-?B Pathway
27/09/2023 -
Abstract To screen microRNAs (miRNAs) and analyze their role in the nasopharyngeal carcinoma (NPC) development through differential analysis and cytological validation of the...
Facile synthesis of MOF-derived N doped ZnO/C nanoparticles and its adsorption activity toward dye removal
27/09/2023 -
Metal–organic framework (MOF)-derived materials have gained an increasing interest and showed potential adsorption features in numerous applications. Significant attempts have been performed to...
A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes
27/09/2023 -
Nature, Published online: 25 September 2023; doi:10.1038/s41586-023-06651-yDistinguishing features of Long...
Evaluating socioeconomic inequalities in influenza vaccine uptake during the COVID-19 pandemic: A cohort study in Greater Manchester, England
27/09/2023 -
Background There are known socioeconomic inequalities in annual seasonal influenza (flu) vaccine uptake. The Coronavirus Disease 2019 (COVID-19) pandemic was associated with multiple factors that...
NAD+-Dependent Formate Dehydrogenase from Themotolerant Yeast Ogataea parapolymorpha: Properties and Protein Engineering of the N-Terminal Sequence
27/09/2023 -
Abstract Previously, the gene of formate dehydrogenase (FDH, EC 1.2.1.2) from the thermotolerant methylotrophic yeast Ogataea parapolymorpha DL 1 (OpaFDH) was cloned in our...
A reliable numerical investigation of an SEIR model of measles disease dynamics with fuzzy criteria
27/09/2023 -
https://www.nature.com/articles/s41598-023-42953-x
Machine learning strategy for identifying altered gut microbiomes for diagnostic screening in myasthenia gravis
27/09/2023 -
Myasthenia gravis (MG) is a neuromuscular junction disease with a complex pathophysiology and clinical variation for which no clear biomarker has been discovered. We hypothesized that because...
COVID vaccines linked to unexpected vaginal bleeding
27/09/2023 -
Nature, Published online: 25 September 2023; doi:10.1038/d41586-023-02987-7It could have shown vision and...
Recommendations on data sharing in HIV drug resistance research
27/09/2023 -
Author summary?•?Human immunodeficiency virus (HIV) drug resistance has implications for antiretroviral treatment strategies and for containing the HIV pandemic because the development of HIV drug...
CRISPR/Cas9-Mediated Genome Editing of the Komagataella phaffii to Obtain a Phytase-Producer Markerless Strain
27/09/2023 -
Abstract Using CRISPR/Cas9 system, the recipient strains K. phaffii VKPM Y-5013 (His– phenotype) and K. phaffii VKPM Y-5014 (Leu– phenotype) were derived from the...
