Biotecnología
Biotecnología
Recent advancements in flavonoid production through engineering microbial systems
23/07/2024 -
Abstract Flavonoids are a class of polyphenolic compounds found in plants that offer extensive health benefits and have applications in the pharmaceutical, cosmetic, and food...
Production of chitosan from Aspergillus niger and quantitative evaluation of the process using adapted analytical tools
23/07/2024 -
Abstract The chitosan production process from fishery waste is already established in industrial scale, whereby fungal chitosan is produced in lower amounts. Since fungal chitosan...
Advancing biofoundry development: strategies and challenges
23/07/2024 -
Abstract This study explores the development of biofoundries, emphasizing the integration of synthetic biology with artificial intelligence (AI) and robotics. It outlines critical...
Extraction of the outer membrane protein pertactin from Bordetella pertussis with urea for the production of acellular pertussis vaccine
23/07/2024 -
Abstract Pertactin (PRN), a non-fimbrial outer membrane protein of Bordetella pertussis, is the limiting component of the acellular pertussis vaccine because of its low...
Cell-free supernatant-assisted biogenic silver nanoparticles enhance the antibacterial efficacy of communicating bacterial pathogens
23/07/2024 -
Abstract The use of nanoparticles (NPs) as an alternative to the current generation of conventional antibiotics has exploded in the research community in recent years, as evidence...
Enhanced production of lactic acid from pretreated rice straw using co-cultivation of Bacillus licheniformis and Bacillus sonorenesis
10/07/2024 -
Abstract Lactic acid (LA) production from sugar mixture derived from lignocellulosic rice straw employing co- culture system of thermotolerant and inhibitor tolerant Bacillus...
Imaging without barriers | Science
13/05/2024 -
Low-field magnetic resonance imaging can be engineered for widespread point-of-care diagnostics
La posible prohibición de TikTok tiene nerviosos a los comunicadores científicos de EE. UU.
24/03/2024 -
Los defensores dicen que la plataforma ofrece educación gratuita a una amplia audiencia, así como un flujo de ingresos fundamental.
Resumen del año 2023 por Nature Methods
23/01/2024 -
tifier>doi:10.1038/s41592-023-02158-6 Nature Methods, Published online: 2024-01-11; | doi:10.1038/s41592-023-02158-6 2024-01-11 Nature Methods 10.1038/s41592-023-02158-6...
G-quadruplex structural dynamics at MAPK12 promoter dictates transcriptional switch to determine stemness in breast cancer
19/01/2024 -
Abstract P38? (MAPK12) is predominantly expressed in triple negative breast cancer cells (TNBC) and induces stem cell (CSC) expansion resulting in decreased survival of the...
Hemorrhagic Activity of Cationic Starch Conjugates with Sterically Hindered Phenol after Intravenous Administration to Guinea Pigs
19/01/2024 -
Intravenous injection of cationic starch conjugated with sterically hindered phenol (terpenophenol) to guinea pigs did not increase hemorrhagic activity (in doses of 2 and 4 mg/kg) and plasma...
The Effect of Original Russian Neurotropic Drugs on Organic Anion Transporting Polypeptides OATP1B1 and OATP1B3
19/01/2024 -
In experiments on HepG2 cells, we studied the effect of the original domestic neurotropic drugs omberacetam, fabomotizole, and ethylmethylhydroxypyridine succinate (EMHPS) (1-500 ?M) on the...
Pulsatile Features of Major Arteries in Rats during Hypotension Caused by Acute Blood Loss
19/01/2024 -
The study examined the modes of pulsations of the femoral and carotid arteries of rats in situ (n=14) during acute blood loss, which sequentially caused a deep BP drop, cardiac and respiration...
Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids
19/01/2024 -
Abstract N-methyl-d-aspartate receptors (NMDARs) play a critical role in normal brain function, and variants in genes encoding NMDAR subunits have been described in individuals...
The Influence of Adiponectin on Transport of Low-Density Lipoproteins through Human Endothelial Cell Monolayer In Vitro
19/01/2024 -
The influence of adiponectin, a protein secreted by adipocytes, on the activation of transendothelial LDL transport, the initial event of atherogenesis, was studied. The addition of adiponectin to...
Increasing HbA1c is associated with reduced CD8+ T cell functionality in response to influenza virus in a TCR-dependent manner in individuals with diabetes mellitus
19/01/2024 -
Abstract Diabetes mellitus is on the rise globally and is a known susceptibility factor for severe influenza virus infections. However, the mechanisms by which diabetes...
The Search for Diagnostic Criteria to Divide the Wistar Rat Population into Phenotypes during Modeling of Post-Traumatic Stress Disorder
19/01/2024 -
The levels of circulating hormones (corticosterone, testosterone, and leptin) and interleukins were studied in sexually mature male Wistar rats against the background of post-traumatic stress...
Indicators of LPO and Antioxidant Protection in Rats During Long-Term Restriction of Motor Activity
19/01/2024 -
This article presents a comprehensive study of the parameters of LPO (concentrations of malondialdehyde, diene conjugates, and intensity of chemiluminescence) and antioxidant defense...
Splenectomy ameliorates liver cirrhosis by restoring the gut microbiota balance
19/01/2024 -
Abstract Background Dysbiosis of gut microbiota is frequent in liver cirrhosis (LC) patients, and splenectomy (SP) has been reported...
Age-Related Features of the Early Period of Liver Regeneration after Partial Hepatectomy in Rats
19/01/2024 -
Regenerative processes in the liver were studied in 3-month-old (young) and 9-month-old (aged) male Wistar rats on day 1 after 30 and 70% hepatectomy. Regardless of the resected liver volume,...
Early endocannabinoid-mediated depolarization-induced suppression of excitation delays the appearance of the epileptic phenotype in synapsin II knockout mice
19/01/2024 -
Abstract The mechanism underlying the transition from the pre-symptomatic to the symptomatic state is a crucial aspect of epileptogenesis. SYN2 is a member of a multigene family...
