Biotecnología

Biotecnología

IMPRESCINDIBLE

Partículas similares a virus para la administración de fármacos: una revisión de métodos y aplicaciones

13/09/2022 - Las partículas similares a virus (VLP) son estructuras versátiles para aplicaciones de administración de fármacos. Las mutaciones en las proteínas estructurales de VLP pueden mejorar la administración de fármacos de VLP. La carga, liberación y activación de carga VLP son características clave para la administración de fármacos.

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Células senescentes en ingeniería de tejidos

06/06/2022 - Las células senescentes (SnC), es decir, las células que han entrado en una detención permanente del ciclo celular, ejercen poderosos efectos celulares no autónomos en sus entornos locales. Como tales, las SnC influyen en el destino y las patologías de las células en el tejido adulto, incluso en entornos donde los ingenieros de tejidos han dirigido sus esfuerzos. Aquí, comparamos las SnC transitorias en la reparación de tejidos, en contraste con las SnC crónicas en la patología osteoartrítica y la respuesta a cuerpos extraños..

IMPRESCINDIBLE

Plant-Based Meat Analogues from Alternative Protein: A Systematic Literature Review

19/09/2022 - This study aimed to conduct a systematic literature review (SLR) of the research performed in the plant-based meat analogues area. Historical, current, and future tendencies are discussed. The paper offers a comprehensive SLR coupled with a bibliometric analysis of the publication from 1972 to January 2022. The articles were obtained using a research string and precise inclusion and exclusion criteria from two prominent databases, Scopus and Web of Science (WoS). The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow technique was used to describe the data screening and selection. In total, 84 publications were selected for further analysis after a thorough literature assessment. From this study, six main themes were identified: (1) objectives of the study; (2) type of plant protein; (3) product type; (4) added ingredients; (5) texturization technique; and (6) quality assessment considered in the studies. Recent trends in publication imply that meat analogue technology is gaining prominence. This review revealed significant research on improving meat analogues via texturization. Even though extrusion is used industrially, the technique is still in its infancy and needs improvement. Future studies should focus more on fiber and protein–protein interactions, macromolecule conformation and mechanisms, diversifying or improving current methods, sensory attributes, and gastrointestinal absorption rate of each novel protein ingredient.

Influence of Extracellular Vesicles from the Follicular Fluid of Young Women and Women of Advanced Maternal Age with Different miRNA Profiles on Sperm Functional Properties
19/09/2022 - We studied the effect of co-culturing of extracellular vesicles in the follicular fluid of young women and women of advanced maternal age on sperm motility. Vesicles were obtained by differential...
The Multifaceted Relationship between the COVID-19 Pandemic and the Food System
19/09/2022 - Panyong Congou black tea (PCT) is one of the most representative and historically famous Congou black teas in China and has been gaining more and more attention for its beneficial health properties....
Contribution of insect gut microbiota and their associated enzymes in insect physiology and biodegradation of pesticides
19/09/2022 - Synthetic pesticides are extensively and injudiciously applied to control agriculture and household pests worldwide. Due to their high use, their toxic residues have enormously increased in the...
3-Dimensional coculture of breast cancer cell lines with adipose tissue–Derived stem cells reveals the efficiency of oncolytic Newcastle disease virus infection via labeling technology
19/09/2022 - Oncolytic virotherapy is one of the emerging biological therapeutics that needs a more efficient in vitro tumor model to overcome the two-dimensional (2D) monolayer tumor cell culture model’s...
Effects of aflatoxin B1 on growth performance, antioxidant status, immune response, and pro-inflammatory cytokine mRNA expression in ISA chicks
19/09/2022 - The research evaluated the effects of Aflatoxin B1 on growth performance, antioxidant status, immune response, and pro-inflammatory cytokine mRNA expression in ISA chicks. In total, 240 7-day-old...
Community science draws on the power of the crowd
19/09/2022 - Nature, Published online: 12 September 2022; doi:10.1038/d41586-022-02936-wHow to keep within Earth’s limits,...
Transit facility allocation: Hybrid quantum-classical optimization
19/09/2022 - An essential consideration in urban transit facility planning is service efficiency and accessibility. Previous research has shown that reducing the number of facilities along a route may increase...
Evaluating profitability of beef cattle farming and its determinants among smallholder beef cattle farmers in the Baljovan District of Khatlon region, Tajikistan
19/09/2022 - In Tajikistan, owning beef cattle is an important survival mechanism for smallholder farmers to alleviate poverty. Therefore, beef cattle farming enterprises should indeed strive to maximize profit...
Antimicrobial metabolite of Cordyceps tenuipes targeting MurE ligase and histidine kinase via in silico study
19/09/2022 - Abstract Cordyceps spp. are widely healthy foods around the world with several traditional uses and bio-functionalities. The chemical characterization of ethyl acetate–soluble...
Regulation of fenestra formation via actin-dynamin2 interaction in rat pituitary endothelial cells
19/09/2022 - Abstract Endothelial fenestrae are transcellular pores divided by a diaphragm consisting of plasmalemma vesicle-associated protein (PLVAP). They function as a channel for peptide...
Chemical Composition and Antioxidant Capacity of the Fruits of European Plum Cultivar “Čačanska Lepotica” Influenced by Different Rootstocks
19/09/2022 - The development of organic agriculture has been promoted worldwide to improve the nutritional health of families, and Ecuador is no exception. The aim of this research was to identify the behaviour...
Impacts of Cold Plasma Technology on Sensory, Nutritional and Safety Quality of Food: A Review
19/09/2022 - The SARS-CoV-2 pandemic is being questioned for its possible food transmission, due to several reports of the virus on food, outbreaks developed in food companies, as well as its origins linked to...
A Refined Supervision Model of Rice Supply Chain Based on Multi-Blockchain
19/09/2022 - Zucchini fruit are highly sensitive to low temperatures leading to significant peel depressions, increasing weight loss and making them impossible to be commercialized. In this study the effect on...
Pathogenic variation types in human genes relate to diseases through Pfam and InterPro mapping
19/09/2022 - Grouping residue variations in a protein according to their physicochemical properties allows a dimensionality reduction of all the possible substitutions in a variant with respect to the wild...
A comparison of different established and novel methods to determine horses' laterality and their relation to rein tension
19/09/2022 - The present study aimed to assess an agreement between established and novel methods to determine laterality and to identify the distribution of laterality in warmbloods and Thoroughbreds. Nine...
Exploratory lipidome and metabolome profiling contributes to understanding differences in high and normal ultimate pH beef
19/09/2022 - https://www.sciencedirect.com/science/article/pii/S0309174022002467?dgcid=rss_sd_allhttps://www.sciencedirect.com/science/article/pii/S0309174022002467Content and gain of macro minerals in the empty...