Biotecnología

Biotecnología

Lactic acid production from food waste: Advances in microbial fermentation and separation technologies
08/11/2024 - China generates over 100 million tons of food waste annually, leading to significant environmental pollution and health risks if not managed properly. Converting FW into a high-value-added platform...
Status and future developments for downstream processing of biological products
14/08/2024 - AbstractIn the burgeoning field of proteins, the effective analysis of intricate protein data remains a formidable challenge, necessitating advanced computational tools for data processing,...
Reinforcement learning based temperature control of a fermentation bioreactor for ethanol production
14/08/2024 - AbstractAdaptive laboratory evolution (ALE) is a widely used microbial strain development and optimization method. ALE experiments, to select for faster?growing strains, are commonly performed as...
Enzyme purification and sustained enzyme activity for pharmaceutical biocatalysis by fusion with phase?separating intrinsically disordered protein
14/08/2024 - AbstractCold?induced vasoconstriction is a significant contributor that leads to chilblains and hypothermia in humans. However, current animal models have limitations in replicating cold?induced...
Engineering a versatile yeast platform for sesquiterpene production from glucose or methanol
14/08/2024 - Graphical Abstract and Lay SummaryA major challenge for the biopharmaceutical industry is instability of transgene expression, where epigenetic repression silences genes encoding high?value products....
Predictive modeling for cell culture in commercial manufacturing of biotherapeutics
14/08/2024 - An experimental and computational approach for the prediction of single cell Lmm?A assembly changes and nuclear viscosity alterations after microfluidic compression stresses.AbstractIn recent years,...
Aconitum lycoctonum L. (Ranunculaceae) mediated biogenic synthesis of silver nanoparticles as potential antioxidant, anti-inflammatory, antimicrobial and antidiabetic agents
03/10/2023 - In this study, a polar extract of Aconitum lycoctonum L. was used for the synthesis of silver nanoparticles (AgNPs), followed by their characterization using different techniques and evaluation of...
Fragment merging approach for design, synthesis, and biological assessment of urea/acetyl hydrazide clubbed thienopyrimidine derivatives as GSK-3? inhibitors
03/10/2023 - New thienopyrimidine derivatives were designed and synthesized as GSK-3? inhibitors based on the structure of active binding site of GSK-3? enzyme. In this study, compounds 6b and 6a were found to be...
Higher sensitive selective spectrofluorometric determination of ritonavir in the presence of nirmatrelvir: application to new FDA approved co-packaged COVID-19 pharmaceutical dosage and spiked human plasma
27/09/2023 - Ritonavir was recently combined with nirmatrelvir in a new approved co-packaged medication form for the treatment of COVID-19. Quantitative analysis based on fluorescence spectroscopy measurement was...
Influence of body mass index on recurrence of atrial fibrillation after electrical cardioversion
27/09/2023 - Background Several studies have shown an independent relationship between body mass index (BMI) and the incidence of atrial fibrillation (AF). However, little is known about the influence of BMI...
Development of a sustainable multianalyte MEKC method for quantitation of the antihyperlipidemic drugs ezetimibe together with three statins. Greenness and whiteness appraisal studies
27/09/2023 - Implementing powerful and sustainable research that complies with green analytical chemistry (GAC) and white analytical chemistry (WAC) fundamentals can downsize the environmental compliance costs...
The effects of different biochars on <i>Caenorhabditis elegans</i> and the underlying transcriptomic mechanisms
27/09/2023 - Different biochars have diverse properties, with ambiguous effects on soil nematodes. This study investigated how aspen sawdust (ABC), bamboo powder (BBC), maize straw (MBC) and peanut-shell biochars...
Comparative physicochemical, hormonal, transcriptomic and proteomic analyses provide new insights into the formation mechanism of two chemotypes of <i>Pogostemon cablin</i>
27/09/2023 - Patchouli (Pogostemon cablin) is an aromatic plant, and its oil has diverse applications in medicine, food, and cosmetics. Patchouli alcohol is the principal bioactive constituent of its...
Factors that influence safe water drinking practices among older persons in slums of Kampala: Analyzing disparities in boiling water
27/09/2023 - Introduction Safe drinking water practice is a key public health promotion strategy for reducing the spread of waterborne diseases. The purpose of this study was to investigate the factors that...
Enzymatic synthesis of novel pyrrole esters and their thermal stability
27/09/2023 - In the present work a simple enzymatic approach (Novozym 435) for transesterification to synthesize pyrrole esters was reported. To generate the best reaction conditions, which resulted in the...
A novel Data and Model Centric artificial intelligence based approach in developing high-performance Named Entity Recognition for Bengali Language
27/09/2023 - Named Entity Recognition (NER) plays a significant role in enhancing the performance of all types of domain specific applications in Natural Language Processing (NLP). According to the type of...
“It saved me from the emergency department”: A qualitative study of patient experience of virtual urgent care in Ontario
27/09/2023 - Introduction In response to the COVID-19 pandemic, the Ontario Ministry of Health introduced a pilot program of 14 virtual urgent care (VUC) initiatives across the province to encourage physical...
Adipose-derived stem cells significantly increases collagen level and fiber maturity in patient-specific biological engineered blood vessels
27/09/2023 - Tissue engineering has driven significant research in the strive to create a supply of tissues for patient treatment. Cell integration into engineered tissues maximizes functional capabilities,...
Non-Immunoglobulin Synthetic Binding Proteins for Oncology
27/09/2023 - Abstract Extensive application of technologies like phage display in screening peptide and protein combinatorial libraries has not only facilitated creation of new recombinant...
Internet search analysis on the treatment of rheumatoid arthritis: What do people ask and read online?
27/09/2023 - Objectives This study aimed to characterize the content of frequently asked questions about the treatment of rheumatoid arthritis (RA) on the internet in Japan and to evaluate the quality of...