Biotecnología

Biotecnología

Activation of CTU2 expression by LXR promotes the development of hepatocellular carcinoma
22/04/2024 - Abstract Cytosolic thiouridylase 2 (CTU2) is an enzyme modifying transfer RNAs post-transcriptionally, which has been implicated in breast cancer and melanoma development. And...
Interaction of functionalized graphene with cellular membranes: an in silico investigation of graphene-based nanovehicle toward biomedical applications
22/04/2024 - Nanomaterials, especially graphene derivatives, have become major tools in the biomedical area. Understanding the way that graphene interacts with component elements of biological systems, like...
Exploring the Role of Ferroptosis-Related Circular RNAs in Subarachnoid Hemorrhage
22/04/2024 - Abstract Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular event associated with high mortality and significant morbidity. Recent studies have highlighted the...
<i>Spilanthes filicaulis</i> (Schumach. & Thonn.) C.D. Adams leaves protects against streptozotocin-induced diabetic nephropathy
22/04/2024 - Background and objective Diabetic neuropathy (DN) is a complex type of diabetes. The underlying cause of diabetic nephropathy remains unclear and may be due to a variety of pathological conditions...
Access of older people to primary health care in low and middle-income countries: A systematic scoping review
22/04/2024 - Introduction Ensuring access for older people to Primary Health Care (PHC) is vital to achieve universal health coverage, improve health outcomes, and health-system performance. However, older...
Developmental trajectories of GABAergic cortical interneurons are sequentially modulated by dynamic FoxG1 expression levels
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Molecular mechanism underlying SNARE-mediated membrane fusion enlightened by all-atom molecular dynamics simulations
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Harmonic resonance and entrainment of propagating chemical waves by external mechanical stimulation in BZ self-oscillating hydrogels
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Blink and you see it
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
An Eclectic Review on Dicarboxylic Acid Production Through Yeast Cell Factories and Its Industrial Prominence
22/04/2024 - Abstract Dicarboxylic acid (DCA) is a multifaceted chemical intermediate, recoursed to produce many industrially important products such as adhesives, plasticizers, lubricants,...
Bringing satellite and nanotechnologies together: unifying strengths against pollution and climate change
22/04/2024 - Nowadays, we witness remarkable technological progress alongside unprecedented challenges that threaten the delicate balance of our planet’s ecological system. Environmental contamination plays a...
Microneedle-mediated nanomedicine to enhance therapeutic and diagnostic efficacy
22/04/2024 - Nanomedicine has been extensively explored for therapeutic and diagnostic applications in recent years, owing to its numerous advantages such as controlled release, targeted delivery, and efficient...
Potential impact of annual vaccination with reformulated COVID-19 vaccines: Lessons from the US COVID-19 scenario modeling hub
22/04/2024 - Background Coronavirus Disease 2019 (COVID-19) continues to cause significant hospitalizations and deaths in the United States. Its continued burden and the impact of annually reformulated...
Effects of (2<i>R</i>,6<i>R</i>)-hydroxynorketamine in assays of acute pain-stimulated and pain-depressed behaviors in mice
22/04/2024 - Ketamine has been shown to produce analgesia in various acute and chronic pain states; however, abuse liability concerns have limited its utility. The ketamine metabolite...
Needs for a conceptual bridge between biological domestication and early food globalization
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Autoimmunity against melanoma differentiation–associated gene 5 induces interstitial lung disease mimicking dermatomyositis in mice
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
The cAMP signaling module regulates sperm motility in the liverwort Marchantia polymorpha
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Formation of recurring transient Ca2+-based intercellular communities during Drosophila hematopoiesis
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Missing validation of key features in HCN single-channel recordings
22/04/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Rapid induction of dopaminergic neuron-like cells from human fibroblasts by autophagy activation with only 2-small molecules
22/04/2024 - Abstract The dopaminergic neurons are responsible for the release of dopamine. Several diseases that affect motor function, including Parkinson's disease (PD), are rooted in...