Biotecnología
Biotecnología
Role of I182, R187, and K188 Amino Acid Residues in the Catalytic Domain of HIV-1 Integrase in the Processes of Reverse Transcription and Integration
16/04/2024 -
Abstract Structural organization of HIV-1 integrase is based on a tetramer formed by two protein dimers. Within this tetramer, the catalytic domain of one subunit of the first...
Transcriptomic analysis identifies the shared diagnostic biomarkers and immune relationship between Atherosclerosis and abdominal aortic aneurysm based on fatty acid metabolism gene set
16/04/2024 -
Background:Epidemiological research has demonstrated that there is a connection between lipid metabolism disorder and an increased risk of developing arteriosclerosis (AS) and abdominal aortic...
Oxidative Stress-Induced Platelet Apoptosis/Activation: Alleviation by Purified Curcumin via ASK1-JNK/p-38 Pathway
16/04/2024 -
Abstract Platelets are known for their indispensable role in hemostasis and thrombosis. However, alteration in platelet function due to oxidative stress is known to mediate...
Identification of mulberry leaf flavonoids and evaluating their protective effects on H2O2-induced oxidative damage in equine skeletal muscle satellite cells
16/04/2024 -
Introduction: Horses are susceptible to oxidative stress during strenuous endurance exercise, leading to muscle fatigue and damage. Mulberry leaf flavonoids (MLFs) possess significant antioxidant...
Human Blood Serum Counteracts EGFR/HER2-Targeted Drug Lapatinib Impact on Squamous Carcinoma SK-BR-3 Cell Growth and Gene Expression
16/04/2024 -
Abstract Lapatinib is a targeted therapeutic inhibiting HER2 and EGFR proteins. It is used for the therapy of HER2-positive breast cancer, although not all the patients...
Paired metagenomic and chemical evaluation of aflatoxin-contaminated dog kibble
16/04/2024 -
IntroductionIdentification of chemical toxins from complex or highly processed foods can present ‘needle in the haystack’ challenges for chemists. Metagenomic data can be used to guide chemical...
Protective Activity of Inactivated Rabies Vaccine Using Flagellin-Based Adjuvant
16/04/2024 -
Abstract Rabies is a zoonotic disease with high lethality. Most human deaths are associated with the bites received from dogs and cats. Vaccination is the most effective...
Algae as an alternative source of protein in poultry diets for sustainable production and disease resistance: present status and future considerations
16/04/2024 -
Integrating algae into poultry diets offers a promising avenue for enhancing nutrition, boosting sustainability efforts, and potentially stimulating disease resistance. This comprehensive review...
Role of the Gut Microbiome and Bacterial Amyloids in the Development of Synucleinopathies
16/04/2024 -
Abstract Less than ten years ago, evidence began to accumulate about association between the changes in the composition of gut microbiota and development of human...
Integrative analysis of proteomics and lipidomic profiles reveal the fat deposition and meat quality in Duroc × Guangdong small spotted pig
16/04/2024 -
IntroductionThis study aims to explore the important factors affecting the characteristics of different parts of pork.MethodsLipidomics and proteomics methods were used to analyze DAL (differential...
Effect of Focal Adhesion Kinase and Vinculin Expression on Migration Parameters of Normal and Tumor Epitheliocytes
16/04/2024 -
Abstract Focal adhesions (FAs) are mechanosensory structures that transform physical stimuli into chemical signals guiding cell migration. Comprehensive studies postulate...
Force-controlled release of small molecules with a rotaxane actuator
16/04/2024 -
Nature, Published online: 10 April 2024; doi:10.1038/s41586-024-07291-6The effects of sex and androgens on the...
Pro-Inflammatory Activation Suppresses TRAIL-induced Apoptosis of Acute Myeloid Leukemia Cells
16/04/2024 -
Abstract Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) is a promising agent for treatment of AML due to its specific apoptosis-inducing effect on tumor...
Publisher Correction: Decoding chromatin states by proteomic profiling of nucleosome readers
16/04/2024 -
Nature, Published online: 09 April 2024; doi:10.1038/s41586-024-07333-zAuthor Correction: Landscape-scale...
The Impact of Long-Term Hypoxia on the Antioxidant Defense System in the Siberian Frog Rana amurensis
16/04/2024 -
Abstract The Siberian frog Rana amurensis has a uniquely high tolerance to hypoxia among amphibians, as it is able to withstand several months underwater with almost no oxygen...
Double-walled Al-based MOF with large microporous specific surface area for trace benzene adsorption
16/04/2024 -
Nature Communications, Published online: 13 April 2024; doi:10.1038/s41467-024-47615-8Maintaining a healthy...
Overexpression of the limk1 Gene in Drosophila melanogaster Can Lead to Suppression of Courtship Memory in Males
16/04/2024 -
Abstract Courtship suppression is a behavioral adaptation of the fruit fly. When majority of the females in a fly population are fertilized and non-receptive for mating, a...
Investigation of Potential Effects of Some Indole Compounds on the Glutathione S-Transferase Enzyme
16/04/2024 -
Abstract Glutathione S-transferases (GSTs) belong to the superfamily of multifunctional detoxification isoenzymes with an important role in cellular signaling. They can...
The Imidazolium Ionic Liquids Toxicity is Due to Their Effect on the Plasma Membrane
16/04/2024 -
Abstract Ionic liquids (ILs) are organic salts with a low melting point. This is due to the fact that their alkyl side chains, which are covalently connected to the ion,...
Erratum to: Viral Vectors in Gene Replacement Therapy
16/04/2024 -
In this article the funding section was misprinted unintentionally. The funding statement should be corrected as follows: A.D.E. was supported by the Russian Science...
Ecological indicators and biological resources for hydrocarbon rhizoremediation in a protected area
16/04/2024 -
Spillage from oil refineries, pipelines, and service stations consistently leads to soil, food and groundwater contamination. Bacterial-assisted phytoremediation is a non-invasive and sustainable...
