Biotecnología

Biotecnología

Reactive Halogen Species: Role in Living Systems and Current Research Approaches
11/03/2024 - Abstract Reactive halogen species (RHS) are highly reactive compounds that are normally required for regulation of immune response, inflammatory reactions, enzyme function,...
The efficient synthesis and purification of 2?3’- cGAMP from Escherichia coli
11/03/2024 - Agonists of the stimulator of interferon genes (STING) pathway are being explored as potential immunotherapeutics for the treatment of cancer and as vaccine adjuvants for infectious diseases....
The Interplay Between Epilepsy and Parkinson’s Disease: Gene Expression Profiling and Functional Analysis
11/03/2024 - Abstract The results of many epidemiological studies suggest a bidirectional causality may exist between epilepsy and Parkinson’s disease (PD). However, the underlying molecular...
Post-Translational Oxidative Modifications of Hemostasis Proteins: Structure, Function, and Regulation
11/03/2024 - Abstract Reactive oxygen species (ROS) are constantly generated in a living organism. An imbalance between the amount of generated reactive species in the body and their...
Multi-wavelength Raman microscopy of nickel-based electron transport in cable bacteria
11/03/2024 - Cable bacteria embed a network of conductive protein fibers in their cell envelope that efficiently guides electron transport over distances spanning up to several centimeters. This form of...
Photonic chip-based low-noise microwave oscillator
11/03/2024 - Nature, Published online: 06 March 2024; doi:10.1038/s41586-024-07140-6Global profiling of hyper-reactive...
Multicomponent DNAzyme Nanomachines: Structure, Applications, and Prospects
11/03/2024 - Abstract Nucleic acids (NAs) are important components of living organisms responsible for the storage and transmission of hereditary information. They form complex structures...
Identification of bacteria and fungi responsible for litter decomposition in desert steppes via combined DNA stable isotope probing
11/03/2024 - IntroductionSoil microorganisms play crucial roles in determining the fate of litter in desert steppes because their activities constitute a major component of the global carbon (C) cycle. Human...
Ultra-compact quasi-true time delay for boosting wireless channel capacity
11/03/2024 - Nature, Published online: 06 March 2024; doi:10.1038/s41586-024-07134-4A paper reports the development of a...
Formation of Supplementary Metal-Binding Centers in Proteins under Stress Conditions
11/03/2024 - Abstract In many proteins, supplementary metal-binding centers appear under stress conditions. They are known as aberrant or atypical sites. Physico-chemical properties of...
Identification and genomic characterization of Pseudomonas spp. displaying biocontrol activity against Sclerotinia sclerotiorum in lettuce
11/03/2024 - Lettuce is an economically major leafy vegetable that is affected by numerous diseases. One of the most devastating diseases of lettuce is white mold caused by Sclerotinia sclerotiorum. Control...
Subicular neurons encode concave and convex geometries
11/03/2024 - Nature, Published online: 06 March 2024; doi:10.1038/s41586-024-07141-5A multidimensional proteomics analysis...
Fenton Reaction in vivo and in vitro. Possibilities and Limitations
11/03/2024 - Abstract The review considers the problem of hydrogen peroxide decomposition and hydroxyl radical formation in the presence of iron in vivo and in vitro. Analysis of the...
The C-terminal selenenylsulfide of extracellular/non-reduced thioredoxin reductase endows this protein with selectivity to small-molecule electrophilic reagents under oxidative conditions
11/03/2024 - Mammalian cytosolic thioredoxin reductase (TrxR1) serves as an antioxidant protein by transferring electrons from NADPH to various substrates. The action of TrxR1 is achieved via reversible...
Oldest stone tools in Europe hint at ancient humans’ route there
11/03/2024 - Nature, Published online: 06 March 2024; doi:10.1038/d41586-024-00575-xIn experiments dubbed the Random Genome...
Animal Models of FUS-Proteinopathy: A Systematic Review
11/03/2024 - Abstract Mutations that disrupt the function of the DNA/RNA-binding protein FUS could cause amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. One of...
Integrating virtual screening, pharmacoinformatics profiling, and molecular dynamics: identification of promising inhibitors targeting 3CLpro of SARS-CoV-2
11/03/2024 - Introduction: The pursuit of effective therapeutic solutions for SARS-CoV-2 infections and COVID-19 necessitates the repurposing of existing compounds. This study focuses on the detailed...
G-Quadruplexes as Sensors of Intracellular Na+/K+ Ratio: Potential Role in Regulation of Transcription and Translation
11/03/2024 - Abstract Data on the structure of G-quadruplexes, noncanonical nucleic acid forms, supporting an idea of their potential participation in regulation of gene expression in...
The structural properties of full-length annexin A11
11/03/2024 - Annexin A11 (ANXA11) is a calcium-dependent phospholipid-binding protein belonging to the annexin protein family and implicated in the neurodegenerative amyotrophic lateral sclerosis....
Biomolecular Condensates: Structure, Functions, Methods of Research
11/03/2024 - Abstract The term “biomolecular condensates” is used to describe membraneless compartments in eukaryotic cells, accumulating proteins and nucleic acids. Biomolecular...