Biotecnología

Biotecnología

Hyperbaric Oxygen Upregulates Mst1 to Activate Keap1/Nrf2/HO-1 Pathway Resisting Oxidative Stress in a Rat Model of Acute Myocardial Infarction
26/02/2024 - Abstract This study aimed to investigate the protective effects and mechanisms of hyperbaric oxygen (HBO) preconditioning in a rat model of acute myocardial infarction (MI)...
Catechol- and thiol-containing binder that aggregates granular xenografts in reconstructed bone defects by mimicking mussel wet adhesion
26/02/2024 - Abstract Xenograft bone granules are bone graft materials that are widely used to reconstruct bone tissue in clinical practice, and their clinical success requires aggregation...
MicroRNAs Associated with Keloids Identified by Microarray Analysis and In Vitro Experiments
26/02/2024 - Abstract MicroRNAs (miRNAs) play a crucial role in gene regulation and the development of keloid. This research aimed to identify and verify miRNAs associated with keloids by...
Targeted siRNA delivery to lung epithelia reduces airway inflammation in a mouse model of allergic asthma
26/02/2024 - Abstract Asthma is a chronic inflammatory disease triggered by allergic reactions in the bronchia. These reactions lead to swelling of mucous membranes, hypersecretion of mucus,...
Super-additive cooperation
26/02/2024 - Nature, Published online: 21 February 2024; doi:10.1038/s41586-024-07089-6Studies using genetic screening,...
Development and optimization of a modular two-fragment LacI switch for enhanced biosensor applications
26/02/2024 - Abstract Being able to perform modular design of artificial transcription factors is useful in bioengineering and synthetic biology, particularly in the development of biosensors...
The life and gruesome death of a bog man revealed after 5,000 years
26/02/2024 - Nature, Published online: 21 February 2024; doi:10.1038/d41586-024-00520-yMassive environmental DNA project...
Vibrio species as next-generation chassis for accelerated synthetic biology
26/02/2024 - Abstract Synthetic biology aims to establish engineering principles for biological systems by leveraging the design-build-test-learn (DBTL) cycle. Central to the success of the...
Daily briefing: Great ‘Stone Age’ wall discovered in Baltic Sea
26/02/2024 - Nature, Published online: 21 February 2024; doi:10.1038/d41586-024-00511-zA system that edits RNA rather than...
Combining metabolic flux analysis with proteomics to shed light on the metabolic flexibility: the case of Desulfovibrio vulgaris Hildenborough
26/02/2024 - IntroductionDesulfovibrio vulgaris Hildenborough is a gram-negative anaerobic bacterium belonging to the sulfate-reducing bacteria that exhibits highly versatile metabolism. By switching from one...
A deep learning-based method for modeling of RNA structures from cryo-EM maps
26/02/2024 - Nature Biotechnology, Published online: 23 February 2024; doi:10.1038/s41587-024-02162-xWe developed a deep...
Electroacupuncture at ST25 corrected gut microbial dysbiosis and SNpc lipid peroxidation in Parkinson’s disease rats
26/02/2024 - IntroductionParkinson’s disease (PD) remains one kind of a complex, progressive neurodegenerative disease. Levodopa and dopamine agonists as widely utilized PD therapeutics have not shown...
OMArk, a tool for gene annotation quality control, reveals erroneous gene inference
26/02/2024 - Nature Biotechnology, Published online: 21 February 2024; doi:10.1038/s41587-024-02155-wWe developed the OMArk...
Oral Clostridium butyricum on mice endometritis through uterine microbiome and metabolic alternations
26/02/2024 - Endometritis occurs frequently in humans and animals, which can negatively affect fertility and cause preterm parturition syndrome. Orally administered Clostridium butyricum, a butyrate-producing...
Harnessing eukaryotic retroelement proteins for transgene insertion into human safe-harbor loci
26/02/2024 - Nature Biotechnology, Published online: 20 February 2024; doi:10.1038/s41587-024-02137-yTransgenes are inserted...
Diosgenin alleviates D-galactose-induced oxidative stress in rats’ brain and liver targeting aging and apoptotic marker genes
26/02/2024 - The theory of aging is primarily concerned with oxidative stress caused by an imbalance in reactive oxygen species generation and cellular antioxidants. To alleviate the oxidative stress, we...
Carbonic anhydrases in the cell wall and plasma membrane of Arabidopsis thaliana are required for optimal plant growth on low CO2
26/02/2024 - Introduction: Plants have many genes encoding both alpha and beta type carbonic anhydrases. Arabidopsis has eight alpha type and six beta type carbonic anhydrase genes. Individual carbonic...
Cooperative control of a DNA origami force sensor
26/02/2024 - https://www.nature.com/articles/s41598-024-53841-3
In the moonlight: non-catalytic functions of ubiquitin and ubiquitin-like proteases
26/02/2024 - Proteases that cleave ubiquitin or ubiquitin-like proteins (UBLs) are critical players in maintaining the homeostasis of the organism. Concordantly, their dysregulation has been directly linked to...
Contribution of protein conformational heterogeneity to NMR lineshapes at cryogenic temperatures
26/02/2024 - Proceedings of the National Academy of Sciences, Volume 121, Issue 8, February 2024.