Biotecnología
Biotecnología
Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes
22/04/2024 -
Background: Dormant ribosomes are typically associated with preservation factors to protect themselves from degradation under stress conditions. Stm1/SERBP1 is one such protein that anchors the 40S...
Novel anti-inflammatory effects of the IL-1 receptor in kidney myeloid cells following ischemic AKI
22/04/2024 -
Introduction: Acute kidney injury (AKI) is one of the most common causes of organ failure in critically ill patients. Following AKI, the canonical pro-inflammatory cytokine interleukin-1? (IL-1?) is...
Unraveling the prognostic significance of RGS gene family in gastric cancer and the potential implication of RGS4 in regulating tumor-infiltrating fibroblast
22/04/2024 -
Regulator of G-protein signaling (RGS) proteins are regulators of signal transduction mediated by G protein-coupled receptors (GPCRs). Current studies have shown that some molecules in the RGS gene...
Proteomic analysis reveals a potential role for extracellular vesicles within the erythroblastic island niche
22/04/2024 -
Introduction: Erythroblastic island (EBI) macrophages play an essential role in the production and maturation of the vast numbers of red blood cells (RBCs) that are produced throughout life. Their...
YTHDC1-Mediated lncRNA MSC-AS1 m6A Modification Potentiates Laryngeal Squamous Cell Carcinoma Development via Repressing ATXN7 Transcription
22/04/2024 -
Abstract Laryngeal squamous cell carcinoma (LSCC) has the highest mortality rate among head and neck squamous cell carcinoma. This study was designed to investigate the biological...
Microneedle-mediated nanomedicine to enhance therapeutic and diagnostic efficacy
22/04/2024 -
Nanomedicine has been extensively explored for therapeutic and diagnostic applications in recent years, owing to its numerous advantages such as controlled release, targeted delivery, and efficient...
WTAP-mediated N6-methyladenine Modification of circEEF2 Promotes Lung Adenocarcinoma Tumorigenesis by Stabilizing CANT1 in an IGF2BP2-dependent Manner
22/04/2024 -
Abstract N6-methyladenosine (m6A) is a common posttranscriptional RNA modification and plays an important role in cancer biology. Circular RNAs (circRNAs) are also reported to...
This water bottle purifies your drink with energy from your steps
22/04/2024 -
Nature, Published online: 17 April 2024; doi:10.1038/s41586-024-07329-9A screen utilizing an environmental DNA...
Performance, kinetic characteristics and bacterial community of short-cut nitrification and denitrification system at different ferrous ion conditions
22/04/2024 -
Abstract In order to explore the operation performance, kinetic characteristics and bacterial community of the short-cut nitrification and denitrification (SND) system, the SND...
We must protect the global plastics treaty from corporate interference
22/04/2024 -
Nature, Published online: 17 April 2024; doi:10.1038/d41586-024-01098-1Virologist Hulda Jónsdóttir studies...
In silico identification of phytochemical inhibitors for multidrug-resistant tuberculosis based on novel pharmacophore generation and molecular dynamics simulation studies
22/04/2024 -
Multidrug-resistant tuberculosis (particularly resistant to pyrazinoic acid) is a life-threatening chronic pulmonary disease. Running a marketed regime specifically targets the ribosomal protein...
Comparative proteomic analysis of papaya bud flowers reveals metabolic signatures and pathways driving hermaphrodite development
22/04/2024 -
https://www.nature.com/articles/s41598-024-59306-x
Identification of new potent NLRP3 inhibitors by multi-level in-silico approaches
22/04/2024 -
Nod-like receptor protein 3 (NLRP-3), is an intracellular sensor that is involved in inflammasome activation, and the aberrant expression of NLRP3 is responsible for diabetes mellitus, its...
The role of the correlated motion(s) of the chromophore in photoswitching of green and red forms of the photoconvertible fluorescent protein mSAASoti
22/04/2024 -
https://www.nature.com/articles/s41598-024-59364-1
Effects of coastal saline-alkali soil on rhizosphere microbial community and crop yield of cotton at different growth stages
22/04/2024 -
Soil salinization is a global constraint that significantly hampers agricultural production, with cotton being an important cash crop that is not immune to its detrimental effects. The rhizosphere...
Chromatography affinity resin with photosynthetically-sourced protein A ligand
22/04/2024 -
https://www.nature.com/articles/s41598-024-59266-2
A synergistic therapy against influenza virus A/H1N1/PR8 by a HA1 specific neutralizing single-domain VL and an RNA hydrolyzing scFv
22/04/2024 -
The emergence of anti-influenza drug-resistant strains poses a challenge for influenza therapy due to mutations in the virus’s surface protein. Recently, there has been increasing interest in...
Hepatocyte regeneration is driven by embryo-like DNA methylation reprogramming
22/04/2024 -
Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
Analysis of fungal diversity in the gut feces of wild takin (Budorcas taxicolor)
22/04/2024 -
IntroductionThe composition of the intestinal microbiome correlates significantly with an animal’s health status. Hence, this indicator is highly important and sensitive for protecting endangered...
Cross-kingdom RNA interference mediated by insect salivary microRNAs may suppress plant immunity
22/04/2024 -
Proceedings of the National Academy of Sciences, Volume 121, Issue 16, April 2024.
HIV-1 envelope facilitates the development of protease inhibitor resistance through acquiring mutations associated with viral entry and immune escape
22/04/2024 -
IntroductionThere is increasing evidence supporting a role for HIV-1 envelope in the development of Protease Inhibitor drug resistance, and a recent report from our group suggested that Env mutations...
