Biotecnología

Biotecnología

MSI1 Stabilizes MACF1 to Inhibit Apoptosis of MC3T3-E1 Cells Induced by High Glucose and Promote Osteogenic Differentiation Through Wnt/?-Catenin Signaling Pathway
30/11/2022 - Abstract Diabetes mellitus (DM) affects bone metabolism and causes osteoporosis. Musashi 1 (MSI1), a member of the Musashi family, regulates protein expression by targeting...
Fluidized or not fluidized? Biophysical characterization of biohybrid lipid/protein/polymer liposomes and their interaction with tetracaine
30/11/2022 - ion>https://www.sciencedirect.com/science/article/pii/S0304416522002057?dgcid=rss_sd_allhttps://www.sciencedirect.com/science/article/pii/S0304416522002057Polyunsaturated ?3 fatty acids prevent the...
Expression of a Copper Activated Xylanase in Yeast: Location of the His-Tag in the Protein Significantly Affects the Enzymatic Properties
30/11/2022 - Abstract A copper activated xylanase produced by E. coli BL21 was expressed in Pichia pastoris using the pGAPZ?B expression vector. Two recombinant GH11 xylanase forms were...
Effects of pre-partum dietary crude protein level on colostrum fat globule membrane proteins and the performance of Hu ewes and their offspring
30/11/2022 - Dietary proteins play important roles in the growth and reproduction of sheep, and the ewe's demand for proteins increases dramatically during late pregnancy. This research aimed to investigate...
Identifying individuals using proteomics: are we there yet?
30/11/2022 - Multi-omics approaches including proteomics analyses are becoming an integral component of precision medicine. As clinical proteomics studies gain momentum and their sensitivity increases,...
Advanced assessment through intact glycopeptide analysis of Infliximab’s biologics and biosimilar
30/11/2022 - Characterization of therapeutic monoclonal antibodies (mAbs) represents a major challenge for analytical sciences due to their heterogeneity associated with post-translational modifications...
Characterization of silk genes in Ephestia kuehniella and Galleria mellonella revealed duplication of sericin genes and highly divergent sequences encoding fibroin heavy chains
30/11/2022 - Silk is a secretory product of numerous arthropods with remarkable mechanical properties. In this work, we present the complete sequences of the putative major silk proteins of E. kuehniella and...
The repertoire of protein-sulfatide interactions reveal distinct modes of sulfatide recognition
30/11/2022 - Sulfatide is an abundant glycosphingolipid in the mammalian nervous system, kidney, trachea, gastrointestinal tract, spleen, and pancreas and is found in low levels in other tissues. Sulfatide is...
Co-crystalization reveals the interaction between AtYchF1 and ppGpp
30/11/2022 - AtYchF1 is an unconventional G-protein in Arabidopsis thaliana that exhibits relaxed nucleotide-binding specificity. The bindings between AtYchF1 and biomolecules including GTP, ATP, and 26S rRNA...
The effect of tuina on ulcerative colitis model mice analyzed by gut microbiota and proteomics
30/11/2022 - Tuina can effectively alleviate ulcerative colitis-related symptoms, but the mechanism of action is unknown. The purpose of this research is to explore potential pathways for the treatment of...
Genomics assisted functional characterization of Bacillus velezensis E as a biocontrol and growth promoting bacterium for lily
30/11/2022 - Lily (Lilium spp.) is one of the most famous ornamental flowers globally. Lily basal rot (also known as root rot or stem rot) and lily gray mold have seriously affected the yield and quality of...
A novel high-throughput approach for transforming filamentous fungi employing a droplet-based microfluidic platform
30/11/2022 - Droplet-based microfluidic technology is a powerful tool for single-cell cultivation and rapid isolation of bacteria, yeasts and algae. However, it has been of limited use for studies of...
Nourishing neonatal piglets with synthetic milk and Lactobacillus sp. at birth highly modifies the gut microbial communities at the post-weaning stage
30/11/2022 - The importance of probiotics in pig production is widely recognized. However, the precise role of probiotics in regulating the gut microbiota of piglets has not been assessed extensively....
High-throughput transcriptomics
30/11/2022 - Scientific Reports, Published online: 29 November 2022; doi:10.1038/s41598-022-23985-1High-throughput...
Diversity, structure, and distribution of bacterioplankton and diazotroph communities in the Bay of Bengal during the winter monsoon
30/11/2022 - The Bay of Bengal (BoB) is conventionally believed to be a low productive, oligotrophic marine ecosystem, where the diazotroph communities presumed to play a vital role in adding “new”...
Discovery of a maximally charged Weyl point
30/11/2022 - Nature Communications, Published online: 30 November 2022; doi:10.1038/s41467-022-35022-wOne of the mechanisms...
TMPRSS2 gene polymorphism common in East Asians confers decreased COVID-19 susceptibility
30/11/2022 - COVID-19 has a wide range of clinical presentations, and the susceptibility to SARS-CoV-2 infection and the mortality rate also vary by region and ethnicity. Here, we found that rs12329760 in the...
Fast-evolving genome regions point to DNA that sets humans apart
30/11/2022 - Nature, Published online: 23 November 2022; doi:10.1038/d41586-022-03766-6Ancient chefs made bitter plants...
Tumor Homing Peptides as Fusion Partners of Therapeutic Proteins for Efficient Delivery to Cancer Cells
30/11/2022 - Abstract for practical protein therapeutics and diagnostics, it is necessary to develop a method that can effectively and specifically deliver proteins into cells. Therefore, the...
Establishment of Transcriptional Gene Silencing Targeting the Promoter Regions of GFP, PDS, and PSY Genes in Cotton using Virus-Induced Gene Silencing
30/11/2022 - Abstract Virus-induced gene silencing (VIGS) by deploying viral-based vectors such as tobacco rattle virus (TRV) is a homology-based gene silencing technique in...
Advances in Synthetic Biology Tools and Engineering of Corynebacterium glutamicum as a Platform Host for Recombinant Protein Production
30/11/2022 - Abstract Corynebacterium glutamicum is a gram-positive and non-pathogenic microorganism that has traditionally been used as a major host for amino acid production. With the rapid...