Biotecnología
Biotecnología
Comparative transcriptome analysis to unveil genes affecting the host cuticle destruction in Metarhizium rileyi
20/09/2023 -
Abstract Insect pathogenic fungi, also known as entomopathogenic fungi, are one of the largest insect pathogenic microorganism communities, represented by Beauveria spp. and...
Mapping brain networks in MPS I mice and their restoration following gene therapy
07/08/2023 -
https://www.nature.com/articles/s41598-023-39939-0
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
23/06/2023 -
Abstract Eukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids....
Yeast of Eden: microbial resistance to glyphosate from a yeast perspective
07/06/2023 -
Abstract First marketed as RoundUp, glyphosate is history’s most popular herbicide because of its low acute toxicity to metazoans and broad-spectrum effectiveness across plant...
Insights from metagenome-assembled genomes on the genetic stability and safety of over-the-counter probiotic products
07/06/2023 -
Abstract The demand for and acceptance of probiotics is determined by their quality and safety. Illumina NGS sequencing and analytics were used to examine eight marketed...
Amyloids and prions in the light of evolution
15/05/2023 -
Abstract Functional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid...
The antifungal effect induced by itraconazole in Candida parapsilosis largely depends on the oxidative stress generated at the mitochondria
05/05/2023 -
Abstract In Candida parapsilosis, homozygous disruption of the two genes encoding trehalase activity increased the susceptibility to Itraconazole compared with the isogenic...
The N-terminal disordered region of ChsB regulates its efficient transport to the hyphal apical surface in Aspergillus nidulans
19/04/2023 -
Abstract In fungi, the cell wall plays a crucial role in morphogenesis and response to stress from the external environment. Chitin is one of the main cell wall components in many...
EU gets first hemophilia B gene therapy
19/04/2023 -
Nature Biotechnology, Published online: 17 April 2023; doi:10.1038/s41587-023-01760-5EU gets first hemophilia B...
A minimal region of the HSP90AB1 promoter is suitable for ubiquitous expression in different somatic tissues with applicability for gene therapy
18/04/2023 -
Huntington’s disease (HD) is a multi-tissue failure disorder for which there is no cure. We have previously shown an effective therapeutic approach limited mainly to the central nervous system,...
Tfs1, transcription elongation factor TFIIS, has an impact on chromosome segregation affected by pka1 deletion in Schizosaccharomyces pombe
14/04/2023 -
Abstract The cAMP-dependent protein kinase (PKA) pathway in Schizosaccharomyces pombe plays an important role in microtubule organization and chromosome segregation. Typically,...
Application of nanotags and nanobodies for live cell single-molecule imaging of the Z-ring in Escherichia coli
10/04/2023 -
Abstract Understanding where proteins are localized in a bacterial cell is essential for understanding their function and regulation. This is particularly important for proteins...
Diverse and dynamic forms of gene regulation by the S. cerevisiae histone methyltransferase Set1
03/04/2023 -
Abstract Gene transcription is an essential and highly regulated process. In eukaryotic cells, the structural organization of nucleosomes with DNA wrapped around histone proteins...
Microfluidics: the propellant of CRISPR-based nucleic acid detection
27/03/2023 -
The functionalization of proteins with DNA through the formation of covalent bonds enables a wide range of biotechnology advancements. For example, single-molecule analytical methods rely on...
Artificial intelligence and machine learning applications in biopharmaceutical manufacturing
27/03/2023 -
Disorders of the synovial joint, such as osteoarthritis (OA) and rheumatoid arthritis (RA), afflict a substantial proportion of the global population. However, current clinical management has not...
Harnessing synthetic biology to develop novel psychedelic therapies
27/03/2023 -
10.1016/j.tibtech.2022.12.003 Trends in Biotechnology 41, 4 (2023) 2022-12-23 Trends in Biotechnology 2022-12-23 41 4 S0167-7799(22)X0005-X Industry highlight ...
Harnessing synthetic biology for mushroom farming
27/03/2023 -
The need for sustainable technological solutions for wastewater management at different scales has led to the emergence of several promising integrated bioelectrochemical technologies in the past...
Morphogenic plasticity: the pathogenic attribute of Candida albicans
27/03/2023 -
Abstract Candida albicans is a commensal organism of the human gastrointestinal tract and a prevalent opportunistic pathogen. It exhibits different morphogenic forms to survive in...
Aptamers targeting SARS-COV-2: a promising tool to fight against COVID-19
27/03/2023 -
Eukaryotic hosts are associated with microbial communities that are critical to their function. Microbiota manipulation using beneficial microorganisms, for example, in the form of animal probiotics...
Genomic analyses of drug-resistant Salmonella enterica serovar Heidelberg strains isolated from meat and related sources between 2013 and 2017 in the south region of Brazil
22/03/2023 -
Abstract Salmonella enterica serovar Heidelberg (S. Heidelberg) is a zoonotic, ubiquitous, and worldwide-distributed pathogen, responsible for gastroenteritis in humans caused by...
Functional characterization and comparative analysis of gene repression-mediating domains interacting with yeast pleiotropic corepressors Sin3, Cyc8 and Tup1
03/03/2023 -
Abstract Transcriptional corepressors Sin3, Cyc8 and Tup1 are important for downregulation of gene expression by recruiting various histone deacetylases once they gain access to...
