Biotecnología

Biotecnología

Why multiple myeloma returns
26/04/2022 - Multiple myeloma, the most common type of bone marrow cancer in Germany, almost always returns, even after initial treatment success. In the majority of cases, the reasons behind this treatment...
Gene network changes associated with cancer onset and progression identify new treatment targets
26/04/2022 - Researchers have identified novel changes in gene network interactions associated with cancer that may lead to new treatment targets for chemotherapy. Their work shows that more than 90 percent of...
Researchers identify genetic cause of endometriosis and reveal potential drug target
26/04/2022 - New research offers insight into how to treat endometriosis. The researchers performed genetic analyses of humans and rhesus macaques to identify a specific gene, NPSR1, that increases risk of...
Computer drug simulations offer warning about promising diabetes and cancer treatment
26/04/2022 - Using computer drug simulations, researchers have found that doctors need to be wary of prescribing a promising treatment for all types of cancer and patients.
Study on genetic changes in neuroblastoma
26/04/2022 - When cells within a single tumor differ in terms of their genetic makeup, this is referred to as intratumor heterogeneity. Researchers have been able to reconstruct the process by which this genetic...
Teaching an old dog new tricks: An existing drug opens new possibilities for treating childhood leukemia
26/04/2022 - A new study has shown that the tumor-inhibiting gene TET2 is silenced in a large fraction of cases of acute lymphoblastic leukemia (ALL) in children. The scientists show that the gene can be...
How well do boosters work? Depends on your genes
26/04/2022 - Genetics play an important role in how our bodies respond to vaccines and booster shots, suggesting that certain protective responses elicited by vaccination could be more effective with...
Doctoral student finds alternative cell option for organs-on-chips
26/04/2022 - Organ-on-a-chip technology has provided a push to discover new drugs for a variety of rare and ignored diseases for which current models either don't exist or lack precision. In particular,...
Cardiovascular disorder genetic testing in children presents unique challenges
26/04/2022 - Genetic testing for cardiovascular disorders is rapidly expanding, including among children. In its first scientific statement focused on the issue of cardiovascular genetic testing specifically...
Researchers create personalized organoid models for rare spinal cancer
26/04/2022 - A new study adds to a growing body of evidence that organoids -- lab-grown collections of cells that mimic a patient's tumor -- are a promising avenue for drug discovery to improve outcomes in...
Measuring cancer cell state can reveal drug susceptibility
26/04/2022 - Pancreatic cancer cells can exist in, and transition between, three different cell states, according to new research. These states respond differently to a variety of cancer drugs, and altering the...
New advances for treating non-small cell lung cancer
26/04/2022 - A new publication highlights recent breakthrough therapies developed to treat non-small cell lung cancer (NSCLC). The goal of the study is to provide views on how basic science advances will impact...
Large study of whole genome sequencing data reveals 'treasure trove' of clues about causes of cancer
26/04/2022 - DNA analysis of thousands of tumours from patients has found a 'treasure trove' of clues about the causes of cancer, with genetic mutations providing a personal history of the damage and...
Researchers develop model to predict treatment response in gastric cancer
26/04/2022 - A study is validating the use of genomic sequencing to predict the likelihood that patients with gastric cancer will derive benefit from chemotherapy or from immunotherapy.
ALS therapy should target brain, not just spine
26/04/2022 - The brain is indeed a target for treating ALS (amyotrophic lateral sclerosis), scientists have discovered. This flips a long-standing belief the disease starts in the spinal motor neurons and any...
Novel therapy shows promise for lung cancer patients with rare EGFR mutation
26/04/2022 - Researchers report on a multinational, early phase clinical trial evaluating a new targeted therapy for patients with metastatic or unresectable non-small cell lung cancer who have a specific genetic...
Cellular diversity of esophageal tissue revealed
26/04/2022 - Researchers have defined 11 subsets of cells found in the esophagus of mice, information that could potentially help clinicians diagnose or treat certain types of cancer.
Researchers find trove of proteins that may influence cystic fibrosis
26/04/2022 - Researchers have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.
Researchers link new gene variant in Amish population to lower risk of heart disease
26/04/2022 - Researchers have discovered a new gene variant associated with lower levels of heart-damaging LDL cholesterol and a blood clotting protein called fibrinogen that appears to significantly lower a...
Healthy lifestyle may help mitigate high genetic risk of cancer
26/04/2022 - Healthy lifestyle factors such as abstinence from smoking and drinking, low body mass index, and exercise correlated with decreased cancer incidence, even in individuals with a high genetic risk.
An immune ‘fingerprint’ reveals path for better treatment of autoimmune diseases
26/04/2022 - Most autoimmune diseases are easy to diagnose but hard to treat. A new article proposes using your unique immune cell fingerprint to rapidly identify which treatments will work for your autoimmune...